Lautenbacher S, Pauls A M, Strian F, Pirke K M, Krieg J C
Department of Psychiatry, Max Planck Institute for Psychiatry, Munich, Federal Republic of Germany.
Biol Psychiatry. 1991 Jun 1;29(11):1073-8. doi: 10.1016/0006-3223(91)90249-l.
Pain threshold was measured with short heat stimuli using a contact thermode in 19 patients with anorexia nervosa, 20 patients with bulimia nervosa, and 21 control subjects. Both patient groups had significantly elevated pain thresholds compared with the control subjects. In the total sample, no substantial covariation could be demonstrated among pain threshold and clinical, physiological, metabolic, or psychological data. However, in separate regression analyses pain threshold correlated significantly (negatively) with local skin temperature in the anorectic patients and almost significantly (positively) with body weight in the bulimic patients. This finding suggests that the reduced pain sensitivity in the two kinds of eating disorders might have different causes.
使用接触式热电极,通过短时间热刺激对19名神经性厌食症患者、20名神经性贪食症患者和21名对照受试者进行疼痛阈值测量。与对照受试者相比,两组患者的疼痛阈值均显著升高。在整个样本中,未发现疼痛阈值与临床、生理、代谢或心理数据之间存在显著的协变关系。然而,在单独的回归分析中,神经性厌食症患者的疼痛阈值与局部皮肤温度显著负相关,神经性贪食症患者的疼痛阈值与体重几乎显著正相关。这一发现表明,两种饮食失调症中疼痛敏感性降低的原因可能不同。