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表现为全前房积血的视网膜母细胞瘤：三年随访

Retinoblastoma presenting as total hyphema: Three year follow-up.

作者信息

Zafar Saemah Nuzhat, Zaheer Naima, Khan Mumtaz Ahmad

机构信息

Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.

Fauji Foundation Hospital, Rawalpindi, Pakistan.

出版信息

Saudi J Ophthalmol. 2017 Oct-Dec;31(4):272-274. doi: 10.1016/j.sjopt.2017.03.006. Epub 2017 Apr 4.

DOI:10.1016/j.sjopt.2017.03.006
PMID:29234233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5717497/
Abstract

Retinoblastoma very rarely presents as total hyphema. Our patient presented at an early age of 7 months. Follow-up of 3 years shows that unilateral group E retinoblastoma was treated successfully with enucleation and adjuvant chemotherapy. The fellow eye remained normal during this period. The factors associated with delay in treatment are also described. Reports like the present case add to the information available about advanced staging of retinoblastoma at the time of presentation, seen in cases with spontaneous hyphema due to the tumor.

摘要

视网膜母细胞瘤极少表现为全前房积血。我们的患者在7个月大时就出现了这种情况。3年的随访显示，单侧E组视网膜母细胞瘤通过眼球摘除术和辅助化疗得到了成功治疗。在此期间，对侧眼保持正常。文中还描述了与治疗延迟相关的因素。像本病例这样的报告增加了我们对视网膜母细胞瘤就诊时晚期分期情况的了解，这种情况可见于因肿瘤导致自发性前房积血的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51b7/5717497/6c4874d05c5d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51b7/5717497/5557f69be09b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51b7/5717497/6c4874d05c5d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51b7/5717497/5557f69be09b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51b7/5717497/6c4874d05c5d/gr2.jpg

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本文引用的文献

1
Knowledge of genetics in familial retinoblastoma.家族性视网膜母细胞瘤的遗传学知识。
Ophthalmic Genet. 2017 May-Jun;38(3):226-232. doi: 10.1080/13816810.2016.1195846. Epub 2016 Jul 18.
2
Retinoblastoma: An overview.视网膜母细胞瘤：概述
Saudi J Ophthalmol. 2014 Oct;28(4):310-5. doi: 10.1016/j.sjopt.2013.11.001. Epub 2013 Nov 21.
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Anterior segment retinoblastoma detectable on magnetic resonance imaging.磁共振成像可检测到的前段视网膜母细胞瘤。
Retin Cases Brief Rep. 2010 Summer;4(3):243-5. doi: 10.1097/ICB.0b013e3181a59e04.
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Characteristics and clinical presentations of pediatric retinoblastoma in North-western Iran.伊朗西北部儿童视网膜母细胞瘤的特征与临床表现
Int J Ophthalmol. 2012;5(4):510-2. doi: 10.3980/j.issn.2222-3959.2012.04.20. Epub 2012 Aug 18.
5
Hyphema revealing retinoblastoma in childhood. A case report.
Bull Soc Belge Ophtalmol. 2011(318):41-3.
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Clinical predictors of high risk histopathology in retinoblastoma.视网膜母细胞瘤高危组织病理学的临床预测因素。
Pediatr Blood Cancer. 2012 Mar;58(3):356-61. doi: 10.1002/pbc.23239. Epub 2011 Jun 30.
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Ultrasound biomicroscopy evaluation of anterior extension in retinoblastoma: a clinicopathological study.超声生物显微镜评估视网膜母细胞瘤的前向延伸：一项临床病理研究。
Br J Ophthalmol. 2012 Mar;96(3):337-40. doi: 10.1136/bjophthalmol-2011-300051. Epub 2011 May 23.
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Retinoblastoma presenting as spontaneous hyphema.以自发性前房积血为表现的视网膜母细胞瘤。
Can J Ophthalmol. 2007 Jun;42(3):489.
9
Systemic metastasis following hyphema drainage in an unsuspected retinoblastoma.未被怀疑的视网膜母细胞瘤前房积血引流后的全身转移。
J Pediatr Ophthalmol Strabismus. 2007 Mar-Apr;44(2):120-3. doi: 10.3928/01913913-20070301-06.
10
Atypical presentations of retinoblastoma.视网膜母细胞瘤的非典型表现。
J Pediatr Ophthalmol Strabismus. 2004 Jan-Feb;41(1):18-24. doi: 10.3928/0191-3913-20040101-06.