新西兰溶剂暴露的汽车碰撞修复工人的神经心理表现。

Neuropsychological performance in solvent-exposed vehicle collision repair workers in New Zealand.

作者信息

Keer Samuel, Glass Bill, McLean Dave, Harding Elizabeth, Babbage Duncan, Leathem Janet, Brinkmann Yanis, Prezant Bradley, Pearce Neil, Douwes Jeroen

机构信息

Centre for Public Health Research, Massey University, Wellington, New Zealand.

Centre for eHealth & Centre for Person Centred Research, Auckland University of Technology, Auckland, New Zealand.

出版信息

PLoS One. 2017 Dec 13;12(12):e0189108. doi: 10.1371/journal.pone.0189108. eCollection 2017.

DOI:10.1371/journal.pone.0189108

PMID:29236771

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5728539/

Abstract

OBJECTIVES

To assess whether contemporary solvent exposures in the vehicle collision repair industry are associated with objectively measured neuropsychological performance in collision repair workers.

METHODS

The RBANS battery and additional tests were administered to 47 vehicle collision repair and 51 comparison workers randomly selected from a previous questionnaire study.

RESULTS

Collision repair workers performed lower on tests of attention (digit span backwards: -1.5, 95% CI -2.4, -0.5; digit span total: -1.7, CI -3.3, -0.0; coding: -6.1, CI -9.9, -2.8; total attention scale: -9.3, CI -15.9, -2.8) and the RBANS total scale (-5.1, CI -9.1, -1.2). Additional tests also showed deficits in visual attention and reaction time (Trails B: -11.5, CI -22.4, -0.5) and motor speed/dexterity (coin rotation dominant hand & non-dominant: -2.9, CI -5.3, -0.4 and -3.1, CI -5.6, -0.7 respectively). The strongest associations were observed in panel beaters. Applying dichotomised RBANS outcomes based on the lowest percentile scores of a normative comparison group showed strongly increased risks for attention (5th percentile: OR 20.1, 95% CI 1.5, 263.3; 10th percentile: 8.8, CI 1.7, 46.2; and 20th percentile: 5.1, CI 1.5, 17.6, respectively). Those employed in the industry for ≤ 17 years (the median work duration) generally had lower scores in the attention domain scale and RBANS total scale compared to those employed >17 years suggesting a healthy worker survivor bias, but trends were inconsistent for other domains.

CONCLUSIONS

This study has found significant deficits in cognitive performance in collision repair workers despite low current airborne exposures in New Zealand.

摘要

目的

评估汽车碰撞修复行业中当前的溶剂暴露是否与碰撞修复工人客观测量的神经心理表现相关。

方法

对从先前问卷调查研究中随机选取的47名汽车碰撞修复工人和51名对照工人进行RBANS测验及其他测试。

结果

碰撞修复工人在注意力测试（倒背数字跨度：-1.5，95%置信区间-2.4，-0.5；数字跨度总和：-1.7，置信区间-3.3，-0.0；译码：-6.1，置信区间-9.9，-2.8；总注意力量表：-9.3，置信区间-15.9，-2.8）和RBANS总量表（-5.1，置信区间-9.1，-1.2）上表现较差。其他测试还显示视觉注意力和反应时间存在缺陷（连线测验B：-11.5，置信区间-22.4，-0.5）以及运动速度/灵活性方面（优势手和非优势手旋转硬币：分别为-2.9，置信区间-5.3，-0.4和-3.1，置信区间-5.6，-0.7）。在车身修理工中观察到的关联最强。根据正常对照组最低百分位数得分应用二分法的RBANS结果显示，注意力风险大幅增加（第5百分位数：比值比20.1，95%置信区间1.5，263.3；第10百分位数：8.8，置信区间1.7，46.2；第20百分位数：5.1，置信区间1.5，17.6）。与工作超过17年的人相比，在该行业工作≤17年（工作时长中位数）的人在注意力领域量表和RBANS总量表上的得分通常较低，这表明存在健康工人幸存者偏差，但其他领域的趋势不一致。