Wilk Christopher M, Gold James M, Humber Kathy, Dickerson Faith, Fenton Wayne S, Buchanan Robert W
Maryland Psychiatric Research Center, PO Box 21247, Baltimore, MD 21228-0747, USA.
Schizophr Res. 2004 Oct 1;70(2-3):175-86. doi: 10.1016/j.schres.2003.10.009.
The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a brief, standardized cognitive screening instrument that assesses several domains of interest and offers an efficient approach to screening for cognitive impairment in schizophrenia (SC). Prior studies have established the clinical validity and test-retest reliability of the RBANS in SC.
The purpose of the current study was to guide clinical interpretation by providing normative data for the use of the RBANS as a measure of cognitive impairment in SC. We also sought to evaluate the role of demographic factors and to present percentile data accordingly.
575 patients (391 male, 184 female) meeting the diagnostic criteria for SC or schizoaffective disorder were recruited from 4 inpatient (n=117) and 6 outpatient (n=458) sites in 2 different mental health treatment systems. All participants were administered the RBANS according to standardized instructions and a subgroup of 242 patients were also administered the Wide Range Achievement Test (3rd Edition) (WRAT-3) Reading subtest.
RBANS Total Scale score for patients with SC was approximately 2 standard deviations below the normal mean, was approximately 1 standard deviation below WRAT-3 Reading scores, and expected patterns of impairment were observed: measures of language and visuospatial ability were preserved relative to those of memory and attention. Aside from weak associations with Language (0.139) and Attention (0.112), age was not significantly associated with RBANS Index scores (which are age adjusted in healthy controls). Education was significantly associated with all RBANS scores and one-way ANOVA indicates that those with more than high school education scored consistently higher than the other two groups (less than and equal to a complete high school education). Normative tables with age and education based percentiles are presented.
The RBANS is an efficient screening tool for assessing cognitive impairment in patients with SC thereby making it a useful instrument for clinical and research applications.
用于评估神经心理状态的可重复成套测验（RBANS）是一种简短的标准化认知筛查工具，可评估多个感兴趣的领域，并为精神分裂症（SC）认知障碍的筛查提供了一种有效的方法。先前的研究已经确立了RBANS在SC中的临床效度和重测信度。
本研究的目的是通过提供RBANS作为SC认知障碍测量指标的常模数据来指导临床解释。我们还试图评估人口统计学因素的作用，并相应地呈现百分位数数据。
从2个不同心理健康治疗系统的4个住院部（n = 117）和6个门诊部（n = 458）招募了575名符合SC或精神分裂情感性障碍诊断标准的患者（391名男性，184名女性）。所有参与者均按照标准化指导语接受RBANS测试，242名患者的亚组还接受了广泛成就测验（第3版）（WRAT - 3）阅读子测验。
SC患者的RBANS总量表得分比正常均值低约2个标准差，比WRAT - 3阅读得分低约1个标准差，并且观察到预期的损害模式：相对于记忆和注意力测量，语言和视觉空间能力测量得以保留。除了与语言（0.139）和注意力（0.112）的弱相关性外，年龄与RBANS指数得分无显著相关性（健康对照组的指数得分已根据年龄进行调整）。教育程度与所有RBANS得分均显著相关，单因素方差分析表明，受过高中以上教育的患者得分始终高于其他两组（高中及以下学历）。给出了基于年龄和教育程度百分位数的常模表。
RBANS是评估SC患者认知障碍的有效筛查工具，因此使其成为临床和研究应用中的有用工具。
