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单纯布比卡因:用于脊髓镇痛时选用0.5%还是0.25%?

Plain bupivacaine: 0.5% or 0.25% for spinal analgesia?

作者信息

Nielsen T H, Kristoffersen E, Olsen K H, Larsen H V, Husegaard H C, Wernberg M

机构信息

Department of Anaesthesia, University Hospital of Aarhus, Denmark.

出版信息

Br J Anaesth. 1989 Feb;62(2):164-7. doi: 10.1093/bja/62.2.164.

Abstract

Plain 0.5% bupivacaine 3 ml was compared with plain 0.25% bupivacaine 6 ml for spinal anaesthesia during transurethral surgery in 40 patients. The solutions were injected over 30 s at the L3/4 space with the patient in the sitting position. The patient was kept sitting for 2 min, supine for 5 min and then placed in the lithotomy position. No significant differences were found in onset time, extent of cephalad spread, duration of sensory or motor blockade, or side effects. The use of a 0.5% plain solution of bupivacaine did not appear to confer any advantage over the 0.25% solution.

摘要

在40例经尿道手术患者中,比较了3毫升0.5%布比卡因原液与6毫升0.25%布比卡因原液用于脊髓麻醉的效果。患者取坐位,在L3/4间隙于30秒内注射上述溶液。患者保持坐位2分钟,然后仰卧5分钟,随后置于截石位。在起效时间、向头侧扩散范围、感觉或运动阻滞持续时间或副作用方面未发现显著差异。使用0.5%布比卡因原液似乎并不比0.25%溶液有任何优势。

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