• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

源自结肠子宫内膜异位症的子宫内膜样腺癌。

Endometrioid adenocarcinoma arising from colon endometriosis.

作者信息

Palla Viktoria-Varvara, Karaolanis Georgios, Bliona Theodora, Katafigiotis Ioannis, Anastasiou Ioannis, Hassiakos Demetrios

机构信息

Faculty of Medicine, Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Athens, Greece.

Faculty of Medicine, Vascular Unit, 1st Department of Surgery, Natinal and Kapodistrian University of Athens, Athens, Greece.

出版信息

SAGE Open Med Case Rep. 2017 Dec 5;5:2050313X17745204. doi: 10.1177/2050313X17745204. eCollection 2017.

DOI:10.1177/2050313X17745204
PMID:29238580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5721959/
Abstract

Endometriosis-associated intestinal tumors represent the malignant transformation of gastrointestinal endometriosis. Approximately 50 cases have been reported in the literature. They are most commonly found among women aged 30-60 years, whereas exogenous hormone therapy and obesity are primary risk factors for the malignant transformation of endometriotic lesions. Clinical features simulate a primary colonic carcinoma. A high index of suspicion in conjunction with careful histological and immunohistochemical examination (CK7, CK20, CDX2, CD10, ER, and PR) is important for establishing a correct diagnosis. In this article, a rare case of a postmenopausal woman with no risk factors and conflicting clinical presentation, diagnosed with endometriosis-associated intestinal tumor, is described.

摘要

子宫内膜异位症相关肠道肿瘤是胃肠道子宫内膜异位症的恶性转化。文献中已报道约50例。它们最常见于30至60岁的女性,而外源性激素治疗和肥胖是子宫内膜异位病变恶性转化的主要危险因素。临床特征类似原发性结肠癌。高度怀疑并结合仔细的组织学和免疫组化检查(CK7、CK20、CDX2、CD10、ER和PR)对于做出正确诊断很重要。本文描述了一例罕见的绝经后女性病例,该患者无危险因素且临床表现相互矛盾,被诊断为子宫内膜异位症相关肠道肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccea/5721959/88fa3ce0b192/10.1177_2050313X17745204-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccea/5721959/88fa3ce0b192/10.1177_2050313X17745204-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccea/5721959/88fa3ce0b192/10.1177_2050313X17745204-fig1.jpg

相似文献

1
Endometrioid adenocarcinoma arising from colon endometriosis.源自结肠子宫内膜异位症的子宫内膜样腺癌。
SAGE Open Med Case Rep. 2017 Dec 5;5:2050313X17745204. doi: 10.1177/2050313X17745204. eCollection 2017.
2
Adenocarcinoma arising in extragonadal endometriosis: an immunohistochemical study.性腺外子宫内膜异位症中发生的腺癌:一项免疫组织化学研究。
Cancer. 1998 Sep 15;83(6):1163-9.
3
Primary sex cord-like variant of endometrioid adenocarcinoma arising from endometriosis.源于子宫内膜异位症的子宫内膜样腺癌的原发性性索样变体。
APMIS. 2008 Sep;116(9):842-5. doi: 10.1111/j.1600-0463.2008.00806.x.
4
Ovarian endometrioid adenocarcinoma arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy for breast cancer: a case report.一名接受他莫昔芬治疗乳腺癌的绝经后女性,因子宫内膜异位囊肿发生卵巢子宫内膜样腺癌:病例报告
Gynecol Oncol. 2002 Nov;87(2):231-4. doi: 10.1006/gyno.2002.6824.
5
A case of clear cell adenocarcinoma arising from endometriosis of the rectum treated by laparoscopic surgery.1例直肠子宫内膜异位症所致透明细胞腺癌经腹腔镜手术治疗的病例。
Int J Surg Case Rep. 2014;5(12):979-83. doi: 10.1016/j.ijscr.2014.10.034. Epub 2014 Oct 23.
6
Endometrioid adenocarcinoma arising from colonic endometriosis mimicking primary colonic carcinoma.起源于结肠子宫内膜异位症的子宫内膜样腺癌,酷似原发性结肠癌。
Int J Gynecol Pathol. 2002 Jul;21(3):285-8. doi: 10.1097/00004347-200207000-00014.
7
An unusual rectosigmoid mass: endometrioid adenocarcinoma arising in colonic endometriosis: case report and literature review.一例罕见的直肠乙状结肠肿物:结肠子宫内膜异位症中发生的子宫内膜样腺癌:病例报告及文献复习
Am Surg. 2005 Aug;71(8):694-7.
8
Primary endometrioid adenocarcinoma of the large intestine arising in colorectal endometriosis.大肠原发性子宫内膜样腺癌起源于大肠子宫内膜异位症。
Histopathology. 2002 Feb;40(2):171-6. doi: 10.1046/j.1365-2559.2002.01313.x.
9
Ovarian yolk sac tumor with endometrioid carcinoma arising from endometriosis in a postmenopausal woman, with special reference to expression of alpha-fetoprotein, sex steroid receptors, and p53.一名绝经后女性患卵巢卵黄囊瘤合并源于子宫内膜异位症的子宫内膜样癌,特别提及甲胎蛋白、性类固醇受体和p53的表达
Gynecol Oncol. 1998 Aug;70(2):295-9. doi: 10.1006/gyno.1998.5048.
10
Metachronic malignant transformation of small bowel and rectal endometriosis in the same patient.同一患者小肠和直肠子宫内膜异位症的异时性恶性转化。
World J Surg Oncol. 2006 Dec 12;4:93. doi: 10.1186/1477-7819-4-93.

引用本文的文献

1
Colonic endometriosis: from subtotal bowel obstruction to malignant transformation - a case series and literature review.结肠子宫内膜异位症:从不全性肠梗阻到恶性转化——病例系列及文献综述
World J Surg Oncol. 2025 Jun 11;23(1):230. doi: 10.1186/s12957-025-03888-x.
2
Clinicopathological features of endometriosis‑associated adenocarcinoma of the rectum: A report of two cases.直肠子宫内膜异位症相关腺癌的临床病理特征:两例报告
Oncol Lett. 2024 Aug 30;28(5):523. doi: 10.3892/ol.2024.14656. eCollection 2024 Nov.
3
Endoscopic Appearance and Management of Recto-Sigmoid Endometriosis: Case Report.

本文引用的文献

1
Endometrioid adenocarcinoma arising from endometriosis of the mesenterium of the sigmoid colon.源于乙状结肠系膜子宫内膜异位症的子宫内膜样腺癌。
Jpn J Clin Oncol. 2005 Mar;35(3):154-7. doi: 10.1093/jjco/hyi037.
2
The homeobox intestinal differentiation factor CDX2 is selectively expressed in gastrointestinal adenocarcinomas.同源框肠道分化因子CDX2在胃肠道腺癌中选择性表达。
Mod Pathol. 2004 Nov;17(11):1392-9. doi: 10.1038/modpathol.3800205.
3
Endometrial adenocarcinoma arising from endometriosis of the rectosigmoid colon.源于乙状结肠直肠子宫内膜异位症的子宫内膜腺癌。
直肠乙状结肠子宫内膜异位症的内镜表现与处理:病例报告
Gastroenterology Res. 2018 Aug;11(4):326-328. doi: 10.14740/gr1049w. Epub 2018 Feb 8.
Gynecol Oncol. 2002 Aug;86(2):220-2. doi: 10.1006/gyno.2002.6643.
4
Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases.细胞角蛋白7和细胞角蛋白20在上皮性肿瘤中的表达:435例病例的调查
Mod Pathol. 2000 Sep;13(9):962-72. doi: 10.1038/modpathol.3880175.
5
Hyperestrogenism: a relevant risk factor for the development of cancer from endometriosis.高雌激素血症:子宫内膜异位症发展为癌症的一个相关风险因素。
Gynecol Oncol. 2000 Oct;79(1):18-22. doi: 10.1006/gyno.2000.5905.
6
Endometriosis-associated intestinal tumors: a clinical and pathological study of 6 cases with a review of the literature.子宫内膜异位症相关肠道肿瘤:6例临床病理研究并文献复习
Hum Pathol. 2000 Apr;31(4):456-63. doi: 10.1053/hp.2000.6712.
7
Endometrial cancer thirteen years after total abdominal hysterectomy and bilateral salpingo-oophorectomy and hormone replacement therapy: a case report.全腹子宫切除术、双侧输卵管卵巢切除术及激素替代治疗十三年后发生子宫内膜癌:一例报告
Eur J Gynaecol Oncol. 1997;18(6):482-3.
8
Endometrial stromal sarcoma arising in pelvic endometriosis in a patient receiving unopposed oestrogen therapy.一名接受单一雌激素治疗的患者,盆腔子宫内膜异位症并发子宫内膜间质肉瘤。
Br J Obstet Gynaecol. 1996 Dec;103(12):1252-4. doi: 10.1111/j.1471-0528.1996.tb09639.x.
9
Less frequent causes of lower gastrointestinal bleeding.下消化道出血的少见病因。
Gastroenterol Clin North Am. 1994 Mar;23(1):21-52.
10
Dioxin pollution and endometriosis in Belgium.
Hum Reprod. 1994 Jun;9(6):1001-2. doi: 10.1093/oxfordjournals.humrep.a138623.