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[血清自发化学发光动力学与肿瘤进程动力学相互关系的实验分析]

[An experimental analysis of the interrelation of the kinetics of spontaneous blood serum chemiluminescence and of the kinetics of the tumor process].

作者信息

Baraboĭ V A, Orel V E

出版信息

Biull Eksp Biol Med. 1989 Feb;107(2):224-6.

PMID:2923982
Abstract

On the material of 5 strains of transplanted rat tumours (sarcoma 45, carcinoma Guérin, carcinosarcoma Walker, lymphosarcoma Pliss, erythromyelosis Shvets) and also mice tumours induced by Moloney and Rauscher viruses and on the models of chemical carcinogenesis of rats: lung (intratracheal injection of 3,4-benz(a)pyrene), breast (DMBA) and liver DENA) was shown that tumorous processes of various origin are accompanied by either elevation or inhibition of blood serum spontaneous chemiluminescence (SChL). In all investigated cases the extreme points of SChL curve coincide with the moment of change of tumour growth kinetics.

摘要

以5株移植性大鼠肿瘤(肉瘤45、格林氏癌、沃克氏癌肉瘤、普利斯氏淋巴肉瘤、什韦茨氏红白血病)以及莫洛尼病毒和劳舍尔病毒诱导的小鼠肿瘤为材料,并以大鼠化学致癌模型:肺(气管内注射3,4-苯并[a]芘)、乳腺(二甲基苯蒽)和肝(二乙基亚硝胺)进行研究,结果表明,各种起源的肿瘤过程都伴随着血清自发化学发光(SChL)的升高或抑制。在所有研究的病例中,SChL曲线的极值点与肿瘤生长动力学变化的时刻一致。

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