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[叙利亚仓鼠原发性和移植性肿瘤模型血液中性粒细胞释放活性氧形式的研究]

[Release of active forms of oxygen by blood neutrophils of Syrian hamsters with primary and transplanted tumors].

作者信息

Kashkina L M, Prilutskaia M O

出版信息

Eksp Onkol. 1988;10(5):73-5.

PMID:3208698
Abstract

The production of reactive oxygen forms by the blood neutrophils of Syrian hamsters bearing primary or transplantable tumours has been studied by chemiluminescence test. It is demonstrated that at the early developmental stages of spontaneous primary lymphosarcomas, or of certain malignant transplantable tumours of different origin there is a significant decrease in the spontaneous chemiluminescence and an increase in phagocytosis-dependent chemiluminescence of blood neutrophils. Such a decrease in the spontaneous chemiluminescence was not observed in hamsters bearing tumours with the low metastatic activity as well as in animals with abscesses.

摘要

通过化学发光试验研究了患有原发性或可移植肿瘤的叙利亚仓鼠血液中性粒细胞中活性氧形式的产生。结果表明,在自发性原发性淋巴肉瘤或某些不同起源的恶性可移植肿瘤的早期发育阶段,血液中性粒细胞的自发化学发光显著降低,而吞噬作用依赖性化学发光增加。在患有低转移活性肿瘤的仓鼠以及患有脓肿的动物中未观察到自发化学发光的这种降低。

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