Murdoch B E, Chenery H J, Kennedy M
Department of Speech and Hearing, University of Queensland, St. Lucia, Australia.
Brain Inj. 1989 Jan-Mar;3(1):41-9. doi: 10.3109/02699058909008072.
A case is presented of a 13-year-old right-handed male who exhibited bilateral striato-capsular lesions following an episode of cerebral anoxia and a range of clinical features typical of aphemia. The findings of a neurological assessment, neuroradiological assessment and battery of speech/language tests are described and their implications for current theories regarding the role of the basal ganglia in speech/language function discussed. The patient initially demonstrated an isolated loss of the ability to articulate words without the loss of the ability to write or comprehend spoken language. His initial mutism later resolved into a dysarthria with features similar to those seen in hypokinetic dysarthria. It was concluded that striato-capsular lesions in childhood are capable of producing temporary language disturbances and in some cases a persistent dysarthria.
本文报告一例13岁右利手男性患者，其在脑缺氧发作后出现双侧纹状体-壳核病变，并伴有一系列典型的运动性失语临床特征。描述了神经学评估、神经放射学评估及一系列言语/语言测试的结果，并讨论了这些结果对当前关于基底神经节在言语/语言功能中作用的理论的影响。患者最初表现为仅丧失清晰说出单词的能力，而书写和理解口语的能力未丧失。其最初的缄默症后来演变为构音障碍，特征与运动减少型构音障碍相似。得出的结论是，儿童期的纹状体-壳核病变能够导致暂时性语言障碍，在某些情况下还会导致持续性构音障碍。
