Li Ye, Li Hepei, He Guanglin, Liang Weibo, Luo Haibo, Liao Miao, Zhang Ji, Yan Jing, Li Yingbi, Hou Yiping, Wu Jin
Institute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Institute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, China.
Leg Med (Tokyo). 2018 Mar;31:14-16. doi: 10.1016/j.legalmed.2017.12.007. Epub 2017 Dec 9.
AGCU 21+1 STR kit contains 21 non-combined DNA index system (non-CODIS) short tandem repeats (STR) loci and a sex-determining locus amelogenin. In this study, we evaluated the genetic diversity and forensically relevant population statistics of 21 non-CODIS loci in 210 Chinese Han individuals from Chengdu city, Sichuan province, Southwest China. No significant deviations from Hardy-Weinberg equilibrium were observed within the 21 non-CODIS STR loci. The combined power of discrimination (CPD) and combined power of exclusion (CPE) were 0.99999999999999999994278, 0.999999355 respectively. To reveal interpopulation differentiations of mainland population of China, a neighbor-joining (N-J) phylogenetic tree was constructed based on Nei's genetic distances among Chengdu Han and 25 published populations. The phylogenetic analyses indicated that Chengdu Han population keeps a close genetic relationship with other Han populations.
AGCU 21+1 STR试剂盒包含21个非联合DNA索引系统（非CODIS）短串联重复序列（STR）基因座和一个用于性别判定的牙釉蛋白基因座。在本研究中，我们评估了来自中国西南部四川省成都市的210名中国汉族个体中21个非CODIS基因座的遗传多样性和法医相关群体统计学数据。在21个非CODIS STR基因座内未观察到显著偏离哈迪-温伯格平衡的情况。联合鉴别力（CPD）和联合排除力（CPE）分别为0.99999999999999999994278、0.999999355。为揭示中国内地人群的群体间差异，基于成都汉族与25个已发表群体之间的Nei遗传距离构建了邻接（N-J）系统发育树。系统发育分析表明，成都汉族群体与其他汉族群体保持着密切的遗传关系。
