Gao Liansheng, Xu Weilin, Li Tao, Luo Huali, Gai Shiying, Xing Ruxin, Chen Gao, Chen Yili
Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou Department of Neurosurgery, Fourth Affiliated Hospital, School of Medicine, Zhejiang University, Yiwu Department of Pathology, Fourth Affiliated Hospital, School of Medicine, Zhejiang University, Yiwu, Zhejiang, China.
Medicine (Baltimore). 2017 Dec;96(49):e8787. doi: 10.1097/MD.0000000000008787.
Primary splenic angiosarcoma (PSA) is a rare, fatal neoplasm originating from sinusoidal vascular endothelial cells, and usually metastasizes and almost always has a poor prognosis. Surgical excision is the main treatment of this highly malignant disease.
We reported a special case of a 68-year-old female who had a 6-month history of scalp masses.
The patient was found to have 2 skull masses on computed tomography (CT). Laboratory findings revealed erythropenia and thrombocytopenia. Enhanced abdomen magnetic resonance imaging (MRI) showed multiple masses in liver and spleen. The pathological result of the skull masses was revealed to be metastatic angiosarcoma.
The patient underwent surgical excision of skull masses, and no subsequent radiotherapy or chemotherapy was done.
The patient died due to dyscrasia at August 12, 2015, with a survival of nearly 1 month.
We highlight the importance for clinicians to be aware of this rare neoplasm, and to consider it in the differential diagnosis when encountering a skull mass. Early confirmation and treatment may improve the prognosis.
原发性脾血管肉瘤（PSA）是一种罕见的致命性肿瘤，起源于窦状血管内皮细胞，通常会发生转移，且预后几乎都很差。手术切除是这种高度恶性疾病的主要治疗方法。
我们报告了一例特殊病例，一名68岁女性，有6个月头皮肿块病史。
计算机断层扫描（CT）发现患者有2个颅骨肿块。实验室检查结果显示红细胞减少和血小板减少。腹部增强磁共振成像（MRI）显示肝脏和脾脏有多个肿块。颅骨肿块的病理结果显示为转移性血管肉瘤。
患者接受了颅骨肿块的手术切除，术后未进行放疗或化疗。
患者于2015年8月12日因血液系统异常死亡，生存期近1个月。
我们强调临床医生认识这种罕见肿瘤的重要性，在遇到颅骨肿块时应将其纳入鉴别诊断。早期确诊和治疗可能会改善预后。
