一例罕见的伴有颅骨肿块、红细胞减少和血小板减少的血管肉瘤：病例报告及文献复习

A rare case of angiosarcoma with skull masses and erythropenia and thrombocytopenia: A case report and review of literature.

作者信息

Gao Liansheng, Xu Weilin, Li Tao, Luo Huali, Gai Shiying, Xing Ruxin, Chen Gao, Chen Yili

机构信息

Department of Neurosurgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou Department of Neurosurgery, Fourth Affiliated Hospital, School of Medicine, Zhejiang University, Yiwu Department of Pathology, Fourth Affiliated Hospital, School of Medicine, Zhejiang University, Yiwu, Zhejiang, China.

出版信息

Medicine (Baltimore). 2017 Dec;96(49):e8787. doi: 10.1097/MD.0000000000008787.

DOI:10.1097/MD.0000000000008787

PMID:29245237

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5728852/

Abstract

RATIONALE

Primary splenic angiosarcoma (PSA) is a rare, fatal neoplasm originating from sinusoidal vascular endothelial cells, and usually metastasizes and almost always has a poor prognosis. Surgical excision is the main treatment of this highly malignant disease.

PATIENT CONCERNS

We reported a special case of a 68-year-old female who had a 6-month history of scalp masses.

DIAGNOSIS

The patient was found to have 2 skull masses on computed tomography (CT). Laboratory findings revealed erythropenia and thrombocytopenia. Enhanced abdomen magnetic resonance imaging (MRI) showed multiple masses in liver and spleen. The pathological result of the skull masses was revealed to be metastatic angiosarcoma.

INTERVENTIONS

The patient underwent surgical excision of skull masses, and no subsequent radiotherapy or chemotherapy was done.

OUTCOMES

The patient died due to dyscrasia at August 12, 2015, with a survival of nearly 1 month.

LESSONS

We highlight the importance for clinicians to be aware of this rare neoplasm, and to consider it in the differential diagnosis when encountering a skull mass. Early confirmation and treatment may improve the prognosis.

摘要