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骨髓活检诊断的脾血管肉瘤:病例报告及文献复习

Splenic Angiosarcoma Diagnosed on Bone Marrow Biopsy: Case Report and Literature Review.

作者信息

Levy Asaph C J, DeFilipp Miriam, Blakely Morgan, Asiry Saeed, Jormark Susan, Goodman Allen

机构信息

Department of Radiology, Northwell Health System, Lenox Hill Hospital, 100 East 77th St, New York, NY 10075 USA.

Department of Pathology, Mount Sinai Hospital Health System, Mount Sinai Hospital, New York, NY 10075 USA.

出版信息

Radiol Case Rep. 2019 Jan 4;14(3):390-395. doi: 10.1016/j.radcr.2018.12.008. eCollection 2019 Mar.

DOI:10.1016/j.radcr.2018.12.008
PMID:30627296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6321865/
Abstract

Primary splenic angiosarcoma carries a poor prognosis and is among the rarest forms of malignancy. An overwhelming majority of patients with splenic angiosarcoma will develop metastases. However, osseous metastatic disease is rare. We present an 83 year old hispanic female who was diagnosed with primary splenic angiosarcoma on bone marrow biopsy performed for a hematologic workup. We highlight key historical, laboratory, imaging, and pathological features of splenic angiosarcoma. The synthesis of both imaging features and clinical history is essential for establishing early diagnosis in these patients.

摘要

原发性脾血管肉瘤预后较差,是最罕见的恶性肿瘤形式之一。绝大多数脾血管肉瘤患者会发生转移。然而,骨转移疾病很少见。我们报告一例83岁的西班牙裔女性,她在进行血液学检查的骨髓活检中被诊断为原发性脾血管肉瘤。我们强调了脾血管肉瘤的关键病史、实验室检查、影像学和病理学特征。综合影像学特征和临床病史对于这些患者的早期诊断至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/d3dbf7fc2345/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/6641b5916568/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/f33177e12477/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/f44a14b9d9f4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/8d53599e0156/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/e8a627aa95a5/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/d3dbf7fc2345/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/6641b5916568/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/f33177e12477/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/f44a14b9d9f4/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/8d53599e0156/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/e8a627aa95a5/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4879/6321865/d3dbf7fc2345/gr6.jpg

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Medicine (Baltimore). 2017 Dec;96(49):e8787. doi: 10.1097/MD.0000000000008787.
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Primary Angiosarcoma of the Spleen: Rare Diagnosis with Atypical Clinical Course.脾脏原发性血管肉瘤:罕见诊断与非典型临床病程
Case Rep Oncol Med. 2016;2016:4905726. doi: 10.1155/2016/4905726. Epub 2016 Oct 27.
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Primary Splenic Angiosarcoma Presenting as Idiopathic Thrombocytopenic Purpura: A Case Report and Review of the Literature.
免疫组化揭示疑似血管肉瘤病例中的骨髓转移
Indian J Hematol Blood Transfus. 2022 Apr;38(2):432-433. doi: 10.1007/s12288-021-01501-1. Epub 2021 Oct 27.
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World J Clin Cases. 2022 Mar 26;10(9):2818-2828. doi: 10.12998/wjcc.v10.i9.2818.
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Splenic Angiosarcoma with Bone Marrow Involvement Initially Diagnosed as Systemic Mastocytosis: A Case Report.
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以特发性血小板减少性紫癜为表现的原发性脾血管肉瘤:一例报告并文献复习
Case Rep Surg. 2016;2016:4173060. doi: 10.1155/2016/4173060. Epub 2016 Aug 29.
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Spontaneous rupture of primary splenic angiosarcoma: A case report.原发性脾血管肉瘤自发性破裂:一例报告。
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Primary splenic angiosarcoma revealed by bone marrow metastasis.骨髓转移提示原发性脾血管肉瘤。
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