Carlson Lindsey C, Hall Timothy J, Rosado-Mendez Ivan M, Palmeri Mark L, Feltovich Helen
Medical Physics Department, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Medical Physics Department, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Ultrasound Med Biol. 2018 Mar;44(3):515-521. doi: 10.1016/j.ultrasmedbio.2017.10.017. Epub 2017 Dec 12.
The aim of this study was to assess the ability of shear wave elasticity imaging (SWEI) to detect changes in cervical softness between early and late pregnancy. Using a cross-sectional study design, shear wave speed (SWS) measurements were obtained from women in the first trimester (5-14 wk of gestation) and compared with estimates from a previous study of women at term (37-41 wk). Two sets of five SWS measurements were made using commercial SWEI applications on an ultrasound system equipped with a prototype catheter transducer (128 elements, 3-mm diameter, 14-mm aperture). Average SWS estimates were 4.42 ± 0.32 m/s (n = 12) for the first trimester and 2.13 ± 0.66 m/s (n = 18) for the third trimester (p <0.0001). The area under the curve was 0.95 (95% confidence interval: 0.82-0.99) with a sensitivity and specificity of 83%. SWS estimates indicated that the third-trimester cervix is significantly softer than the first-trimester cervix. SWEI methods may be promising for assessing changes in cervical softness.
本研究的目的是评估剪切波弹性成像（SWEI）检测妊娠早期和晚期宫颈柔软度变化的能力。采用横断面研究设计，获取了孕早期（妊娠5 - 14周）女性的剪切波速度（SWS）测量值，并与之前一项足月（37 - 41周）女性研究的估计值进行比较。在配备原型导管换能器（128阵元、直径3 mm、孔径14 mm）的超声系统上，使用商用SWEI应用程序进行了两组每组五次的SWS测量。孕早期的平均SWS估计值为4.42±0.32 m/s（n = 12），孕晚期为2.13±0.66 m/s（n = 18）（p <0.0001）。曲线下面积为0.95（95%置信区间：0.82 - 0.99），灵敏度和特异度为83%。SWS估计值表明，孕晚期宫颈明显比孕早期宫颈更柔软。SWEI方法在评估宫颈柔软度变化方面可能很有前景。
