Division of Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil.
Disciplina de Reumatologia, Universidade de São Paulo, Avenida Dr. Arnaldo 455, sala 3142, Cerqueira César, São Paulo, SP, CEP: 01246-903, Brazil.
Rheumatol Int. 2018 Mar;38(3):525-529. doi: 10.1007/s00296-017-3908-x. Epub 2017 Dec 15.
The authors describe the case of a 23-year-old woman who was referred to the rheumatologist due to symmetrical and progressive stiffness, induration, and swelling of arms and thighs at the 12th week of her first gestation. The characteristic clinical aspect of 'peau d'orange', associated to the histopathologic results of the deep biopsy of the skin confirmed the diagnosis of eosinophilic fasciitis. Treatment with oral prednisone, at an initial dose of 1 mg/kg/day, was effective and rapidly tapered to 10 mg/day till the birth of a healthy newborn. A literature review showed only one previous description of pregnancy and eosinophilic fasciitis.
作者描述了一位 23 岁女性的病例，她在首次妊娠的第 12 周时因手臂和大腿对称性、进行性僵硬、硬结和肿胀而被转介到风湿病医生处。“橘皮样外观”的特征性临床特征，结合皮肤深部活检的组织病理学结果，确诊为嗜酸性筋膜炎。口服泼尼松治疗有效，初始剂量为 1mg/kg/天，迅速减至 10mg/天，直至生下一个健康的新生儿。文献复习仅发现一例以前描述的妊娠和嗜酸性筋膜炎病例。
