Centre for Green Chemical Science, University of Auckland, 23 Symonds Street, Auckland, New Zealand.
Department of Chemistry, University of Southampton, Southampton Hampshire, SO17 1BJ, United Kingdom.
ChemSusChem. 2018 Feb 9;11(3):532-535. doi: 10.1002/cssc.201702356. Epub 2018 Jan 5.
A shell biorefinery would involve fractionation of crustacean shells and incorporation of the components into value-added products, particularly those that contain nitrogen. In a proof-of-concept study that validates this concept, the anticancer alkaloid proximicin A has been synthesized from the chitin-derived platform chemical 3-acetamido-5-acetylfuran (3A5AF). This study accentuates the leading role chitin is likely to play in the sustainable production of nitrogen-containing fine chemicals that are not directly attainable from lignocellulose.
贝类生物精炼厂将涉及甲壳类动物外壳的分离，并将这些成分纳入增值产品中，特别是那些含有氮的产品。在一项验证这一概念的概念验证研究中，已经从壳聚糖衍生的平台化学物质 3-乙酰氨基-5-乙酰呋喃（3A5AF）合成了抗癌生物碱 proximicin A。这项研究强调了壳聚糖在可持续生产氮含量精细化学品方面可能发挥的主导作用，而这些化学品无法直接从木质纤维素获得。
