细菌性脑膜炎是发展为注意力缺陷多动障碍的一个风险因素吗？
Is Bacterial Meningitis a Risk Factor for Developing Attention Deficit Hyperactivity Disorder.
作者信息
Hadzic Eldira, Sinanovic Osman, Memisevic Haris
机构信息
Department of Infectious Diseases, Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina.
Department of Neurology, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
出版信息
Isr J Psychiatry. 2017;54(2):54-57.
INTRODUCTION
Bacterial meningitis is a severe disease with high morbidity. Many medical conditions are known to be associated with meningitis including Attention Deficit Hyperactivity Disorder (ADHD). The goal of the present study was to examine the frequency of ADHD in children who had had bacterial meningitis. An additional goal was to assess the odds ratio for ADHD in children who had had meningitis and children who had not had it.
METHODS
The sample comprised 60 children who had had meningitis in the first year of their lives and 60 control children who had not had the disease. ADHD was assessed through the structural clinical interviews with parents according to the criteria set in DSM-IV.
RESULTS
The total frequency of ADHD in children who had had meningitis was 62%, as compared to 5% in children who had not had the disease. The odds ratio for developing ADHD was 30.5 (95% CI = 8.5 to 109) in favor of children in the meningitis group.
CONCLUSION
Meningitis is a significant risk factor for developing ADHD later in childhood. Children who had meningitis need to be monitored for timely detecting and treating ADHD symptoms.
引言
细菌性脑膜炎是一种发病率很高的严重疾病。已知许多医学病症与脑膜炎有关，包括注意力缺陷多动障碍（ADHD）。本研究的目的是检查患过细菌性脑膜炎的儿童中ADHD的发生率。另一个目的是评估患过脑膜炎的儿童与未患过脑膜炎的儿童患ADHD的比值比。
方法
样本包括60名在生命第一年患过脑膜炎的儿童和60名未患该疾病的对照儿童。根据《精神疾病诊断与统计手册》第四版（DSM-IV）设定的标准，通过与家长进行结构化临床访谈来评估ADHD。
结果
患过脑膜炎的儿童中ADHD的总发生率为62%，而未患过该疾病的儿童中这一比例为5%。脑膜炎组儿童患ADHD的比值比为30.5（95%置信区间=8.5至109）。
结论
脑膜炎是儿童后期患ADHD的一个重要危险因素。患过脑膜炎的儿童需要接受监测，以便及时发现和治疗ADHD症状。
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