Pondé Milena Pereira, Novaes Camila Marinho, Losapio Mirella Fiuza
Bahia School of Medicine and Public Health, Salvador, BA, Brazil.
Arq Neuropsiquiatr. 2010 Feb;68(1):103-6. doi: 10.1590/s0004-282x2010000100022.
Both DSM-IV and the ICD-10 exclude diagnosis of attention deficit/hyperactivity disorder (ADHD) when autism diagnostic is present. Some authors suggest, however, that autism can be associated to other comorbidity amongst which the ADHD.
To estimate prevalence of ADHD in children with autism.
Children were selected from a specialized school, all of then had previous diagnosis or diagnostic suspicion of autism. The Brazilian version of the KIDDIE-SADS PL was applied to parents for diagnostic of ADHD. DSM-IV diagnostic of autism was based on parents' interview and child observation.
32 children were included in the study. Results show that 53.1% of the ASD child had ADHD symptoms enough to fulfill DSM-IV diagnostic criteria, whereas 56.9% did not fulfill DSM-IV criteria for ADHD.
Results suggest a high frequency of ADHD symptoms in ASD patients. Elucidating if we are facing a comorbity or an autism distinct phenotype can contribute for a more adjusted pharmacotherapy approach for these children.
《精神疾病诊断与统计手册》第四版（DSM-IV）和《国际疾病分类》第十版（ICD-10）在存在自闭症诊断时均排除注意力缺陷/多动障碍（ADHD）的诊断。然而，一些作者认为，自闭症可能与其他共病有关，其中包括ADHD。
评估自闭症儿童中ADHD的患病率。
从一所特殊学校选取儿童，他们之前均有自闭症的诊断或诊断怀疑。向家长应用巴西版的儿童情感障碍及精神分裂症问卷（KIDDIE-SADS PL）以诊断ADHD。DSM-IV自闭症诊断基于家长访谈和对儿童的观察。
32名儿童纳入研究。结果显示，53.1%的自闭症谱系障碍（ASD）儿童有足以符合DSM-IV诊断标准的ADHD症状，而56.9%不符合ADHD的DSM-IV标准。
结果表明ASD患者中ADHD症状的发生率较高。明确我们面对的是共病还是自闭症的不同表型，有助于为这些儿童采取更合适的药物治疗方法。
