Viñas M, Pineda F, Izquierdo-Domínguez A, Castillo M, Castillo M J, Hernández N, Ibero M
Servicio de Alergia del Consorci Sanitari de Terrassa, Barcelona, Spain Phone: +34 9373 10 007 ext. 1511 E-mail:
Departamento de Aplicaciones, Laboratorio Diater, Madrid, Spain.
Eur Ann Allergy Clin Immunol. 2017 Nov;49(6):281-283. doi: 10.23822/EurAnnACI.1764-1489.21.
We report the case of a 36-year-old male pharmaceutical laboratory worker. On handling Spagulax sachets whose content is a laxative called Plantago ovata, he immediately presented rhinoconjunctivitis. Specific allergy study included SDS-PAGE with Western Blot and specific nasal challenge to Plantago ovata extract. Prick by prick for Spagulax was negative. Total IgE: 126.5 U/mL. Western Blot recognized two proteins of 15 and 20 kDa in the extract of Plantago ovata and three proteins of 15, 18 and 50 kDa in the extract of Plantago lanceolata. We present a case of occupational allergy due to inhalation of and/or contact with Plantago ovata seeds.
我们报告了一名36岁男性制药实验室工作人员的病例。在处理含有名为卵叶车前草的泻药的Spagulax药包时，他立即出现了鼻结膜炎。特异性过敏研究包括用蛋白质印迹法进行的十二烷基硫酸钠-聚丙烯酰胺凝胶电泳以及对卵叶车前草提取物进行的特异性鼻激发试验。对Spagulax进行的逐点刺试验为阴性。总IgE：126.5 U/mL。蛋白质印迹法在卵叶车前草提取物中识别出两种分子量为15 kDa和20 kDa的蛋白质，在窄叶车前草提取物中识别出三种分子量为15 kDa、18 kDa和50 kDa的蛋白质。我们报告了一例因吸入和/或接触卵叶车前草种子而导致的职业性过敏病例。
