Navarrete J, Magliano J, Martínez M, Bazzano C
Cátedra de Dermatología Prof. Dr. Miguel Martínez, Hospital de Clínicas Dr. Manuel Quintela, Universidad de la República, Montevideo, Uruguay.
Cátedra de Dermatología Prof. Dr. Miguel Martínez, Hospital de Clínicas Dr. Manuel Quintela, Universidad de la República, Montevideo, Uruguay.
Actas Dermosifiliogr (Engl Ed). 2018 Apr;109(3):254-261. doi: 10.1016/j.ad.2017.10.007. Epub 2017 Dec 14.
The primary goal of Mohs micrographic surgery (MMS) is to completely excise a cancerous lesion and a wide range of reconstructive techniques of varying complexity are used to close the resulting wound. In this study, we performed a descriptive analysis of patients who underwent MMS, with a focus on wound closure methods.
We conducted a bidirectional descriptive cohort analysis of all MMS procedures performed by a single surgeon between November 2013 and April 2016. Cosmetic outcomes were photographically assessed by a dermatologist after a minimum follow-up of 90 days.
We analyzed 100 MMS procedures in 71 patients with a median age of 73 years. The tumors were basal cell carcinoma (70%), squamous cell carcinoma (29%), and dermatofibrosarcoma protuberans (1%); 75% were located on the head and neck. The reconstructive techniques used were flap closure (48%), simple closure (36%), closure by second intention (11%), and other (5%). Cosmetic outcomes were assessed for 70 procedures (47 patients) and the results were rated as excellent in 20% of cases, very good in 40%, good in 20%, moderate in 17%, and bad/very bad in 2.9%. No significant associations were observed between cosmetic outcome and sex, Fitzpatrick skin type, hypertension, diabetes mellitus, or smoking. Worse outcomes, however, were significantly associated with larger tumor areas and defects, location on the trunk, and flap and second-intention closure.
Although there was a tendency to use simple wound closure for lesions located on the trunk and surgical defects of under 4.4cm, the choice of reconstructive technique should be determined by individual circumstances with contemplation of clinical and tumor-related factors and the preference and experience of the surgeon.
莫氏显微外科手术(MMS)的主要目标是完全切除癌性病变,并采用一系列复杂程度各异的重建技术来闭合由此产生的伤口。在本研究中,我们对接受MMS的患者进行了描述性分析,重点关注伤口闭合方法。
我们对一位外科医生在2013年11月至2016年4月期间进行的所有MMS手术进行了双向描述性队列分析。在至少随访90天后,由皮肤科医生通过照片评估美容效果。
我们分析了71例患者的100例MMS手术,患者中位年龄为73岁。肿瘤类型为基底细胞癌(70%)、鳞状细胞癌(29%)和隆突性皮肤纤维肉瘤(1%);75%位于头颈部。所采用的重建技术为皮瓣闭合(48%)、单纯闭合(36%)、二期愈合闭合(11%)和其他(5%)。对70例手术(47例患者)的美容效果进行了评估,结果评为优秀的占20%,非常好的占40%,好的占20%,中等的占17%,差/非常差的占2.9%。在美容效果与性别、菲茨帕特里克皮肤类型、高血压、糖尿病或吸烟之间未观察到显著关联。然而,较差的结果与较大的肿瘤面积和缺损面积、位于躯干的位置以及皮瓣和二期愈合闭合显著相关。
尽管对于位于躯干且手术缺损小于4.4厘米的病变倾向于采用简单的伤口闭合方法,但重建技术的选择应根据个体情况,综合考虑临床和肿瘤相关因素以及外科医生的偏好和经验来确定。