Lu Yao, Dai Wei, Zong Zhijun, Xiao Yimin, Wu Di, Liu Xuesheng, Chun Wong Gordon Tin
Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Department of Anesthesiology, Affiliated Fuyang Hospital of Anhui Medical University, Hefei, China.
J Cardiothorac Vasc Anesth. 2018 Feb;32(1):297-301. doi: 10.1053/j.jvca.2017.07.026. Epub 2017 Jul 27.
The aim of this study was to compare the quality of lung deflation of a left-sided double-lumen endotracheal tube (DLT) with a bronchial blocker (BB) for one-lung ventilation in video-assisted thoracic surgery (VATS).
A prospective, randomized, clinical study.
A university-affiliated teaching hospital.
Forty-five adult patients undergoing esophageal tumor surgery using VATS with right lung deflation.
Patients were assigned by a computer-generated randomization sequence to either the left-sided DLT or BB group. The correct positioning of the airway device was confirmed using fiberoptic bronchoscopy.
The variables assessed included: (1) time required to correctly place the devices and to achieve lung collapse; (2) the number of times the device malpositioned; (3) the quality of lung deflation as rated by the surgeon; (4) blood pressure and heart rate at baseline (T), immediately before (T) and after (T) and 1 minute (T) after intubation; (5) the number of patients with hypoxemia (SpO < 90%) during the one-lung ventilation (OLV) period; and (6) postoperative hoarseness of voice, sore throat, or pulmonary infection. Of the 45 patients approached for the study, 21 patients in the DLT group and 19 patients in the BB group were analyzed. The time required to place the device in the correct position was similar between the 2 groups. The time to achieve right lung collapse in the BB group was significantly longer (mean difference: 3.232, 95% confidence interval [CI]: 1.993-4.471; p = 0.003). The quality of lung collapse, OLV duration, number of patients with device malposition, and hypoxemia in both groups were similar. There were more patients suffering hoarseness (odds ratio [OR]: 4.85, 95% CI: 1.08-21.76; p = 0.034) or sore throat (OR: 4.29, 95% CI: 1.14-16.18; p = 0.030) in the DLT group, while no patients developed postoperative lung infection in either group. Compared to T, systolic blood pressure (sBP), diastolic BP (dBP), and heart rate (HR) at T in both groups were higher (p < 0.05) in the DLT group. Then, compared to T, sBP and dBP at T and T and HR at T in the DLT group were higher (p < 0.05).
The results of this study showed that BB is an effective alternative for left one-lung ventilation in right VATS, but requires a longer time to achieve complete lung collapse. Moreover, the use of BB caused less hemodynamic perturbation and can reduce postoperative hoarseness and sore throat.
本研究旨在比较左侧双腔气管导管(DLT)与支气管封堵器(BB)在电视辅助胸腔镜手术(VATS)单肺通气时肺萎陷的质量。
一项前瞻性、随机、临床研究。
一所大学附属医院。
45例接受VATS食管癌手术且右肺萎陷的成年患者。
通过计算机生成的随机序列将患者分配至左侧DLT组或BB组。使用纤维支气管镜确认气道装置的正确位置。
评估的变量包括:(1)正确放置装置并实现肺萎陷所需的时间;(2)装置位置错误的次数;(3)外科医生评定的肺萎陷质量;(4)插管前即刻(T)、插管后(T)及插管后1分钟(T)的血压和心率;(5)单肺通气(OLV)期间低氧血症(SpO<90%)患者的数量;(6)术后声音嘶哑、咽痛或肺部感染情况。在纳入研究的45例患者中,分析了DLT组的21例患者和BB组的19例患者。两组放置装置于正确位置所需的时间相似。BB组实现右肺萎陷的时间显著更长(平均差值:3.232,95%置信区间[CI]:1.993 - 4.471;p = 0.003)。两组的肺萎陷质量、OLV持续时间、装置位置错误患者数量及低氧血症情况相似。DLT组声音嘶哑(比值比[OR]:4.85,95% CI:1.08 - 21.76;p = 0.034)或咽痛(OR:4.29,95% CI:1.14 - 16.18;p = 0.030)的患者更多,而两组均无患者发生术后肺部感染。与T时相比,DLT组T时的收缩压(sBP)、舒张压(dBP)和心率(HR)更高(p < 0.05)。然后,与T时相比,DLT组T和T时的sBP和dBP以及T时的HR更高(p < 0.05)。
本研究结果表明,BB是右侧VATS左肺单肺通气的有效替代方法,但实现完全肺萎陷所需时间更长。此外,使用BB引起的血流动力学扰动较小,且可减少术后声音嘶哑和咽痛。