Xiang Ying-Ying, Chen Qi, Tang Xi-Xi, Cao Lei
Department of Anesthesiology, Chongqing Cancer Institute, Chongqing University Cancer Hospital, Chongqing Cancer Hospital, 181# Hanyu Road, Shapingba District, 400030, Chongqing, China.
Department of Anesthesiology, Xinqiao Hospital of Army Military Medical University, 83# Xinqiao Zhengjie, Shapingba District, 400037, Chongqing, China.
BMC Anesthesiol. 2022 Oct 29;22(1):330. doi: 10.1186/s12871-022-01876-2.
This meta-analysis compared the quality of lung collapse and the resultant adverse reactions between the use of double-lumen endotracheal tubes (DLT) and bronchial blockers (BB) in minimally invasive thoracic surgery.
A search was performed in five bibliographic databases, namely PubMed, Springer, Medline, EMBASE, and Cochrane Library ignoring the original language, which identified five randomized controlled trials (RCTs) published on or before December 31, 2021. These studies were subsequently analyzed. All included studies compared the efficacy and safety of DLT and BB as a lung isolation technique in surgery. The methodological quality of each study was assessed by the Cochrane Collaboration's risk of bias tool. The quality of lung collapse and the malposition rate were adopted as the main outcome indicators. Alternatively, the intubation time and the incidence of postoperative sore throat were adopted as secondary indicators.
When either DLT or BB were utilized in minimally invasive thoracic surgery, no differences were observed in the quality of lung collapse (odds ratio [OR], 1.00; 95% confidence interval [CI], 0.63 to 1.58), the intubation time (mean difference [MD], 0.06; 95% CI, -1.02 to 1.14), or the malposition rate (OR, 0.88; 95% CI, 0.37 to 2.06). However, the incidence of postoperative sore throat among patients treated with BB was significantly lower than that among patients treated with DLT (OR, 5.25; 95% CI, 2.55 to 10.75).
When utilized in minimally invasive thoracic surgery, the quality of lung collapse with DLT was identical to that with BB. However, patients treated with the latter demonstrated a significantly lower incidence of postoperative sore throat.
本荟萃分析比较了在微创胸外科手术中使用双腔气管导管(DLT)和支气管封堵器(BB)时肺萎陷的质量及由此产生的不良反应。
在五个文献数据库(即PubMed、Springer、Medline、EMBASE和Cochrane图书馆)中进行检索,忽略原始语言,共识别出2021年12月31日或之前发表的五项随机对照试验(RCT)。随后对这些研究进行分析。所有纳入研究均比较了DLT和BB作为手术中肺隔离技术的有效性和安全性。每项研究的方法学质量通过Cochrane协作网的偏倚风险工具进行评估。将肺萎陷质量和错位率作为主要结局指标。另外,将插管时间和术后咽痛发生率作为次要指标。
在微创胸外科手术中使用DLT或BB时,在肺萎陷质量(优势比[OR],1.00;95%置信区间[CI],0.63至1.58)、插管时间(平均差[MD],0.06;95%CI,-1.02至1.14)或错位率(OR,0.88;95%CI,0.37至2.06)方面未观察到差异。然而,接受BB治疗的患者术后咽痛发生率显著低于接受DLT治疗的患者(OR,5.25;95%CI,2.55至10.75)。
在微创胸外科手术中使用时,DLT导致的肺萎陷质量与BB相同。然而,接受后者治疗的患者术后咽痛发生率显著较低。