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[一例7岁女孩因温州蜜柑果皮中果胶而非果实本身引发过敏反应的病例]

[A CASE OF A 7-YEAR-OLD GIRL WITH ANAPHYLAXIS CAUSED BY PECTIN IN ALBEDO OF CITRUS UNSHIU BUT NOT BY THE FRUIT ITSELF].

作者信息

Uno Hiroshi, Sekimoto Hirokazu, Kitamura Tetsuro

机构信息

Department of Pediatrics, Nippon Kokan Fukuyama Hospital.

出版信息

Arerugi. 2017;66(10):1244-1247. doi: 10.15036/arerugi.66.1244.

DOI:10.15036/arerugi.66.1244
PMID:29249759
Abstract

Pectin is used in several foods as an additive and a thickner. But some cases of anaphylaxis have been reported. Most of these are induced by occasional exposures; however, no cases of anaphylaxis after eating a Citrus unshiu, the albedo of which is rich in pectin, have been reported.A 7-year-old girl developed barking cough and pruritus approximately two hours after eating a frozen Citrus unshiu. She had a history of anaphylaxis induced by consuming cashew nuts. Skin testing and basophil activation tests were performed using a commercially available pectin product. Both tests were positive. In an oral food challenge test, she felt abdominal pain and nausea only after eating fruit, along with the albedo, of Citrus unshiu. We concluded that this case was induced by pectin present in the albedo of Citrus unshiu, but not by the fruit itself. We should consider that patients with cashew nut allergies have a possibility of pectin allergies as well, and that pectin in the albedo of Citrus unshiu may induce anaphylaxis.

摘要

果胶在多种食品中用作添加剂和增稠剂。但已有一些过敏反应的病例报告。其中大多数是由偶尔接触引起的;然而,食用温州蜜柑(其内皮富含果胶)后发生过敏反应的病例尚未见报道。一名7岁女孩在食用冷冻温州蜜柑约两小时后出现犬吠样咳嗽和瘙痒。她有食用腰果诱发过敏反应的病史。使用市售果胶产品进行了皮肤试验和嗜碱性粒细胞活化试验。两项试验均呈阳性。在口服食物激发试验中,她仅在食用带有内皮的温州蜜柑果实后感到腹痛和恶心。我们得出结论,该病例是由温州蜜柑内皮中的果胶引起的,而非果实本身。我们应该考虑到,对腰果过敏的患者也有可能对果胶过敏,并且温州蜜柑内皮中的果胶可能诱发过敏反应。

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