Kwon Younghoon, Kazaglis Louis, Cho Yeilim, Howell Michael J, Mahowald Mark W
Department of Medicine, University of Virginia, 1215 Lee Street, Charlottesville, VA 22908, USA.
Minnesota Regional Sleep Disorders Center, Hennepin County Medical Center, 701 Park Avenue South, Minneapolis, MN 55415, USA.
Sleep Biol Rhythms. 2017 Oct;15(4):337-339. doi: 10.1007/s41105-017-0116-8. Epub 2017 Aug 16.
Reliability of mean sleep latency testing (MSLT) over consecutive days in patients with hypersomnia is unknown. We reviewed MSLTs of patients with hypersomnia without cataplexy who underwent our two consecutive MSLT protocol (N=29). Average MSLs were 10.9 and 10.9 minutes for days 1 and 2, respectively. Agreement for pathological hypersomnia (defined as MSL≤8 minutes) between MSLT days showed k=0.85 for all (N=29) and k=0.76 for those without sleep apnea (N=20). In patients with subjective complaints of hypersomnia, a single MSLT is sufficient (vs. addition of 2 day MSLT) in the setting of carefully implemented protocol controlling for potential confounding variables.
发作性睡病患者连续数天进行平均睡眠潜伏期测试(MSLT)的可靠性尚不清楚。我们回顾了未患猝倒症的发作性睡病患者的MSLT结果,这些患者接受了我们连续两次的MSLT方案(N = 29)。第1天和第2天的平均睡眠潜伏期分别为10.9分钟和10.9分钟。MSLT各天之间病理性发作性睡病(定义为睡眠潜伏期≤8分钟)的一致性显示,所有患者(N = 29)的kappa值为0.85,无睡眠呼吸暂停的患者(N = 20)的kappa值为0.76。对于有发作性睡病主观症状的患者,在精心实施的方案中控制潜在混杂变量的情况下,单次MSLT就足够了(与增加为期2天的MSLT相比)。