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饮酒对肺静脉隔离术后房颤结局的影响。

Impact of Alcohol Consumption on Atrial Fibrillation Outcomes Following Pulmonary Vein Isolation.

作者信息

Barham Waseem Y, Sauer William H, Fleeman Blake, Brunnquell Michael, Tzou Wendy, Aleong Ryan, Schuller Joseph, Zipse Matthew, Tompkins Christine, Nguyen Duy T

机构信息

University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.

出版信息

J Atr Fibrillation. 2016 Dec 31;9(4):1505. doi: 10.4022/jafib.1505. eCollection 2016 Dec.

Abstract

BACKGROUND

Moderate to heavy alcohol use has been shown to be associated with increased atrial fibrillation (AF) incidence. However, the relationship between alcohol use and AF recurrence after pulmonary vein isolation (PVI) is not well known.

OBJECTIVE

We sought to study the impact of different alcohol consumption levels on outcomes after AF ablation.

METHODS

A retrospective analysis was performed of 226 consecutive patients undergoing first time PVI for AF. Clinical data were collected including alcohol intake classified into 3 groups: none-rare (< 1 drink/ week), moderate (1-7 drinks/ week), and heavy (> 7 drinks/ week). Patients were followed for recurrences within the first 3 months (blanking period; early recurrence) and after 3 months up to 1 year (late recurrence) after the ablation.

RESULTS

Paroxysmal and persistent AF had early recurrence rates of 29.1% and 32.2%, and late recurrence rates of 30.2% and 44.1%, respectively. The none-rare alcohol group had a higher frequency of diabetes mellitus (p=0.007). Neither moderate or heavy alcohol consumption, in reference to the none-rare group, was significantly predictive of early or late AF recurrence on adjusted multivariate logistic regression analysis (p>0.05).

CONCLUSION

Despite known associations between alcohol and incidence of AF, alcohol consumption is not associated with early or late AF recurrence after PVI in this cohort.

摘要

背景

已表明中度至重度饮酒与心房颤动(AF)发病率增加有关。然而,饮酒与肺静脉隔离(PVI)后AF复发之间的关系尚不清楚。

目的

我们试图研究不同饮酒水平对AF消融术后结局的影响。

方法

对226例首次因AF接受PVI的连续患者进行回顾性分析。收集临床数据,包括饮酒情况,分为3组:无-极少饮酒(<1杯/周)、中度饮酒(1-7杯/周)和重度饮酒(>7杯/周)。对患者在消融术后的前3个月(空白期;早期复发)和3个月后至1年(晚期复发)进行随访,观察复发情况。

结果

阵发性和持续性AF的早期复发率分别为29.1%和32.2%,晚期复发率分别为30.2%和44.1%。无-极少饮酒组糖尿病发生率较高(p=0.007)。在调整后的多因素逻辑回归分析中,与无-极少饮酒组相比,中度或重度饮酒均不能显著预测AF早期或晚期复发(p>0.05)。

结论

尽管已知饮酒与AF发病率之间存在关联,但在该队列中,饮酒与PVI后AF的早期或晚期复发无关。

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