Hayase Justin, Boyle Noel G
UCLA Cardiac Arrhythmia Center, UCLA Health System,David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
J Atr Fibrillation. 2017 Feb 28;9(5):1508. doi: 10.4022/jafib.1508. eCollection 2017 Feb-Mar.
The implantable cardioverter defibrillator (ICD) is an established therapy for improving mortality for primary and secondary prevention of sudden cardiac death. Whether to perform defibrillation threshold testing (DFT) either intraoperatively or post-operatively remains a controversial issue. The DFT is defined as the minimum energy required at which two shocks can successfully terminate ventricular fibrillation and dates from the era of surgically implanted devices with epicardial patches. Typically, a safety margin of at least 10J is employed for device programming, though some trial data suggest that a margin of 5J could be just as effective. Various methods have been utilized to perform DFT testing, and no particular method has been shown to be superior to another [Figure 1]. Previously, guideline recommendations addressed the indications for ICD implantation but did not comment on DFT testing. Recent consensus statements now provide some guidance as to when it is appropriate to perform or not perform DFT testing in light of new trial data. This review will address some of the risk factors for having a higher DFT, impact of DFT testing on patient outcomes, and some of the risks and contraindications of DFT testing.
植入式心脏复律除颤器(ICD)是一种用于提高心脏性猝死一级和二级预防死亡率的既定疗法。在术中还是术后进行除颤阈值测试(DFT)仍然是一个有争议的问题。DFT被定义为两次电击能够成功终止室颤所需的最小能量,其可追溯到使用心外膜贴片进行手术植入装置的时代。通常,设备编程采用至少10J的安全裕度,不过一些试验数据表明5J的裕度可能同样有效。已经采用了各种方法来进行DFT测试,没有一种特定方法被证明优于其他方法[图1]。以前,指南建议涉及ICD植入的适应症,但未对DFT测试发表评论。最近的共识声明现在根据新的试验数据就何时进行或不进行DFT测试提供了一些指导。本综述将探讨DFT较高的一些风险因素、DFT测试对患者预后的影响以及DFT测试的一些风险和禁忌症。