Department of Psychiatry, Yüzüncü Yıl University School of Medicine, Van, Turkey.
Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.
Psychiatry Res. 2018 Feb;260:391-399. doi: 10.1016/j.psychres.2017.12.026. Epub 2017 Dec 12.
Child maltreatment is a public health issue that is a well-established risk factor for many psychological conditions, including bipolar disorder. The current study is one of the first to investigate associations among child maltreatment, dissociative symptomatology, alexithymia, anxiety, depression, and attachment insecurities. 40 patients with bipolar disorder-I and 40 healthy subjects matched for age, gender, and education participated in the study. The Dissociative Experiences Scale (DES), Somatoform Dissociation Questionnaire (SDQ), Childhood Trauma Questionnaire (CTQ-28), Toronto Alexithymia Scale (TAS-20), Depression Anxiety Stress Scale (DASS-21), and Experiences in Close Relationships-Revised (ECR-R) were completed by participants. In comparison to control participants, patients with bipolar disorder-I reported significantly more frequent abusive experiences in childhood, higher levels of attachment insecurities, more severe pathological and somatoform dissociation, as well as higher scores on measures of alexithymia, anxiety, depression and psychological stress. Reports of psychopathology among first-degree relatives (OR = 102.169, 95%IC = 4.596-2271.255; P < 0.01) and childhood emotional trauma (OR = 1.032; 95%CI = 0.782-1.363, P = 0.05) significantly contributed to bipolar disorder-I diagnosis. In contrast, absorption was negatively associated with bipolar illness (OR = 0.852; 95% CI = 0.747-0.973, P < 0.05). Our results showed significant associations between childhood trauma exposure and risk of bipolar disorder. Moreover, the results demonstrate that emotional abuse exposure predicts bipolar illness.
儿童虐待是一个公共卫生问题,它是许多心理疾病的既定风险因素,包括双相情感障碍。本研究首次调查了儿童虐待、分离症状、述情障碍、焦虑、抑郁和依恋不安全感之间的关联。40 名双相情感障碍 I 型患者和 40 名年龄、性别和教育程度相匹配的健康对照者参加了这项研究。参与者完成了分离体验量表(DES)、躯体化分离问卷(SDQ)、儿童期创伤问卷(CTQ-28)、多伦多述情障碍量表(TAS-20)、抑郁焦虑应激量表(DASS-21)和修订后的亲密关系体验量表(ECR-R)。与对照组相比,双相情感障碍 I 型患者报告称,童年时期遭受虐待的经历更为频繁,依恋不安全感更为严重,病理性和躯体化分离程度更为严重,述情障碍、焦虑、抑郁和心理压力的测量得分也更高。一级亲属的精神病史报告(OR=102.169,95%CI=4.596-2271.255;P<0.01)和童年期情感创伤(OR=1.032;95%CI=0.782-1.363,P=0.05)显著增加了双相情感障碍 I 型的诊断。相反,吸收与双相情感障碍呈负相关(OR=0.852;95%CI=0.747-0.973,P<0.05)。我们的研究结果表明,儿童期创伤暴露与双相情感障碍的发病风险之间存在显著关联。此外,研究结果表明,情感虐待暴露预测双相情感障碍。