Cameron H J, Boila R J, McNichol L W, Stanger N E
Dept of Anim. Sci., University of Manitoba, Winnipeg, Canada.
J Anim Sci. 1989 Jan;67(1):252-61. doi: 10.2527/jas1989.671252x.
Oxidized copper wire, commonly referred to as copper oxide needles (CuON), was evaluated using purebred Hereford cows and their calves. Thirty-seven cows were allocated to Cu treatments of 0, 25 or 50 g CuON (79.9% Cu in CuON) with 12, 12 and 13 cows per treatment, respectively; calves within cow treatments were allocated to treatment of 0 and 20 g CuON. Single oral doses of CuON were given at the start of a grazing trial that lasted 92 d. Cows and calves were weighed and blood samples were taken on d 0, 28, 63 and 92; liver biopsies were taken on d 0, 28 and 92 of the grazing trial. Cattle were consuming grass forage with mean concentrations on d 0, 28, 63 and 92 of the grazing trial ranging from 1.6 to 5.5 mg/kg DM for Cu, 2.5 to 5.5 mg/kg DM for Mo and 1.3 to 1.5 g/kg DM for total S. The water consumed by cattle contained 947 mg sulfate per liter (SE = 13.2, n = 4). Body weight of cows and calves was not influenced (P greater than .05) by CuON. Liver Cu was higher (P less than .01) in treated cows and calves but was not different (P greater than .05) between cows dosed with 25 or 50 g CuON. Treatment of cows and calves with CuON had no influence (P greater than .05) on the concentration of Fe or Mo in liver or plasma, the concentration of Cu and ceruloplasmin activity in plasma, or the concentration of Zn in liver. Plasma Zn did not differ (P greater than .05) in cows, but it was higher (P less than .05) in the calves suckling cows treated with CuON. It was concluded that dosing cows and calves with CuON resulted in a higher Cu content of liver but did not adversely influence the metabolism of Fe or Zn or modify the concentration of Mo in the plasma or liver of cows or calves.
氧化铜线，通常称为氧化铜针（CuON），在纯种赫里福德奶牛及其犊牛身上进行了评估。37头奶牛被分配到0、25或50克CuON（CuON中铜含量为79.9%）的铜处理组，每组分别有12头、12头和13头奶牛；奶牛处理组内的犊牛被分配到0和20克CuON的处理组。在为期92天的放牧试验开始时，单次口服给予CuON。在第0、28、63和92天对奶牛和犊牛进行称重并采集血样；在放牧试验的第0、28和92天进行肝脏活检。在放牧试验的第0、28、63和92天，牛食用的牧草中铜的平均浓度为1.6至5.5毫克/千克干物质，钼为2.5至5.5毫克/千克干物质，总硫为1.3至1.5克/千克干物质。牛饮用的水中每升含有947毫克硫酸盐（标准误=13.2，n=4）。CuON对奶牛和犊牛的体重没有影响（P>0.05）。处理过的奶牛和犊牛肝脏中的铜含量较高（P<0.01），但给予25克或50克CuON的奶牛之间没有差异（P>0.05）。用CuON处理奶牛和犊牛对肝脏或血浆中铁或钼的浓度、血浆中铜和铜蓝蛋白活性的浓度或肝脏中锌的浓度没有影响（P>0.05）。奶牛血浆中的锌没有差异（P>0.05），但用CuON处理的奶牛所哺乳的犊牛血浆中的锌含量较高（P<0.05）。得出的结论是，给奶牛和犊牛投喂CuON会导致肝脏中铜含量升高，但不会对铁或锌的代谢产生不利影响，也不会改变奶牛或犊牛血浆或肝脏中钼的浓度。
