下一代测序技术在临床细菌学中的应用。
Next-generation sequencing applications in clinical bacteriology.
作者信息
Motro Yair, Moran-Gilad Jacob
机构信息
Department of Health System Management, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Public Health Services, Ministry of Health, Jerusalem, Israel.
出版信息
Biomol Detect Quantif. 2017 Oct 23;14:1-6. doi: 10.1016/j.bdq.2017.10.002. eCollection 2017 Dec.
Abstract
With the rapid advances in next generation sequencing (NGS) technologies, clinical and public health microbiology laboratories are increasingly adopting NGS technology in their workflows into their existing diagnostic cycles. In this bacteriology focused review, we review aspects and considerations for applying NGS in the clinical microbiology settings, and highlight the impact of such implementation on the analytical and post-analytical stages of diagnosis.
摘要
随着下一代测序（NGS）技术的迅速发展，临床和公共卫生微生物实验室越来越多地在其工作流程中将NGS技术纳入现有的诊断周期。在这篇聚焦细菌学的综述中，我们回顾了在临床微生物学环境中应用NGS的各个方面及注意事项，并强调了这种应用对诊断分析阶段和分析后阶段的影响。
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