Suppr超能文献

与声门外气道装置围手术期失败相关的可改变和不可改变因素。

Modifiable and Nonmodifiable Factors Associated With Perioperative Failure of Extraglottic Airway Devices.

机构信息

From the Department of Anesthesiology, University of Mississippi Medical Center, Jackson, Mississippi.

Department of Anesthesiology, Washington University in St Louis, St Louis, Missouri.

出版信息

Anesth Analg. 2018 Jun;126(6):1959-1967. doi: 10.1213/ANE.0000000000002659.

Abstract

BACKGROUND

Extraglottic airway device (EGA) failure can be associated with severe complications and adverse patient outcomes. Prior research has identified patient- and procedure-related predictors of EGA failure. In this retrospective study, we assessed the incidence of perioperative EGA failure at our institution and identified modifiable factors associated with this complication that may be the target of preventative or mitigating interventions.

METHODS

We performed a 5-year retrospective analysis of adult general anesthesia cases managed with EGAs in a single academic center. Univariable and multivariable logistic regressions were used to identify clinically modifiable and nonmodifiable factors significantly associated with 3 different types of perioperative EGA failure: (1) "EGA placement failure," (2) "EGA failure before procedure start," and (3) "EGA failure after procedure start."

RESULTS

A total of 19,693 cases involving an EGA were included in the analysis dataset. EGA failure occurred in 383 (1.9%) of the cases. EGA placement failure occurred in 222 (1.13%) of the cases. EGA failure before procedure start occurred in 76 (0.39%) of the cases. EGA failure after procedure start occurred in 85 (0.43%) of the cases. Factors significantly associated with each type of failure and controllable by the anesthesia team were as follows: (1) EGA placement failure: use of desflurane (odds ratio [OR], 1.67; 95% confidence interval [CI], 1.23-2.25) and EGA size 4 or 5 vs 2 or 3 (OR, 0.07; 95% CI, 0.05-0.10); (2) EGA failure before procedure start: use of desflurane (OR, 2.05; 95% CI, 1.23-3.40) and 3 or more placement attempts (OR, 4.69; 95% CI, 2.57-8.56); and (3) EGA failure after procedure start: 3 or more placement attempts (OR, 2.06; 95% CI, 1.02-4.16) and increasing anesthesia time (OR, 1.35; 95% CI, 1.17-1.55).

CONCLUSIONS

The overall incidence of EGA failure was 1.9%, and EGA placement failure was the most common type of failure. We also found that use of desflurane and use of smaller EGA sizes in adult patients were factors under the direct control of anesthesia clinicians associated with EGA failure. An increasing number of attempts at EGA placement was associated with later device failures. Our findings also confirm the association of EGA failure with previously identified patient- and procedure-related factors such as increased body mass index, male sex, and position other than supine.

摘要

背景

会厌下气道装置 (EGA) 故障可导致严重并发症和不良的患者预后。先前的研究已经确定了与 EGA 故障相关的患者和程序相关的预测因素。在这项回顾性研究中,我们评估了我们机构围手术期 EGA 故障的发生率,并确定了与该并发症相关的可修改的因素,这些因素可能是预防或减轻干预的目标。

方法

我们对单家学术中心使用 EGA 管理的成年全身麻醉病例进行了为期 5 年的回顾性分析。采用单变量和多变量逻辑回归分析确定与 3 种不同类型围手术期 EGA 故障(1)“EGA 放置失败”,(2)“程序开始前 EGA 故障”和(3)“程序开始后 EGA 故障”显著相关的临床可修改和不可修改的因素。

结果

共纳入了 19693 例涉及 EGA 的病例,其中 383 例(1.9%)发生了 EGA 故障。EGA 放置失败发生在 222 例(1.13%)病例中。程序开始前发生 EGA 故障 76 例(0.39%)。程序开始后发生 EGA 故障 85 例(0.43%)。与每种失败类型显著相关且可由麻醉团队控制的因素如下:(1)EGA 放置失败:使用地氟烷(比值比[OR],1.67;95%置信区间[CI],1.23-2.25)和 EGA 尺寸 4 或 5 比 2 或 3(OR,0.07;95%CI,0.05-0.10);(2)程序开始前的 EGA 故障:使用地氟烷(OR,2.05;95%CI,1.23-3.40)和 3 次或更多次放置尝试(OR,4.69;95%CI,2.57-8.56);(3)程序开始后 EGA 故障:3 次或更多次放置尝试(OR,2.06;95%CI,1.02-4.16)和麻醉时间延长(OR,1.35;95%CI,1.17-1.55)。

结论

EGA 故障的总体发生率为 1.9%,EGA 放置失败是最常见的失败类型。我们还发现,在成年患者中使用地氟烷和使用较小的 EGA 尺寸是与 EGA 故障相关的直接受麻醉临床医生控制的因素。EGA 放置次数的增加与后期设备故障有关。我们的研究结果还证实了 EGA 故障与先前确定的患者和程序相关因素的关联,例如体重指数增加、男性、仰卧位以外的体位。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验