吸入一氧化二氮可减轻 Caldwell-Luc 手术后患者的疼痛感知：一项随机试验。
Inhaled nitrous oxide can reduce the pain perception in post Caldwell-Luc operation patients-a randomised trial.
机构信息
The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, Wuhan, China.
Department of Oral and Maxillofacial Trauma and Plastic Aesthetic Surgery, School and Hospital of Stomatology, Wuhan University, Wuhan, 430079, People's Republic of China.
出版信息
Sci Rep. 2017 Dec 19;7(1):17760. doi: 10.1038/s41598-017-15731-9.
To assess the efficiency of inhaled nitrous oxide (NO) for the reduce the perception pain in extraction of iodoform gauze packing strips in post Caldwell-Luc operation patients. This randomized single blind trial included a total of 47 patients, aged between 14-82 years, in which undergoing radical maxillary sinusotomy. Based on the randomization procedure, patients were treated with (experimental) or without (control) inhaled NO. The visual analogue scale scores (VAS scores) of the pain perception and the headache duration time were comparatively studied. The average VAS score for pain perception was 3.92 in the NO group and 7.87 in the control group. The average headache duration time was 0.12 hour in the NO group and 13.09 hours in the control group. Both VAS scores for pain perception during the treatment and the average headache duration time were significantly reduced in the inhaled NO group (P < 0.01). Reduced pain perception and headache duration time indicated that, the inhaled NO method might be viable in extraction of iodoform gauze packing strips in post Caldwell-Luc operation patients.
评估吸入一氧化二氮（NO）在减轻 Caldwell-Luc 手术后患者碘仿纱布条取出时疼痛感知的效果。这项随机单盲试验共纳入 47 名年龄在 14-82 岁之间、接受根治性上颌窦切开术的患者。根据随机分组程序，患者接受（实验组）或不接受（对照组）吸入一氧化二氮治疗。比较疼痛感知的视觉模拟评分（VAS 评分）和头痛持续时间。实验组疼痛感知的平均 VAS 评分为 3.92，对照组为 7.87。实验组头痛持续时间平均为 0.12 小时，对照组为 13.09 小时。实验组在治疗期间的疼痛感知 VAS 评分和平均头痛持续时间均显著降低（P<0.01）。疼痛感知降低和头痛持续时间缩短表明，吸入一氧化二氮的方法可能适用于 Caldwell-Luc 手术后患者碘仿纱布条的取出。
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