Barash Alexander, Chou Timothy Y
New York Eye and Ear Infirmary of Mount Sinai, New York, NY 10003, USA.
Am J Ophthalmol Case Rep. 2017 Jun 12;7:62-65. doi: 10.1016/j.ajoc.2017.06.003. eCollection 2017 Sep.
is a rare pathogen. Keratitis from this organism has never been specifically reported or described. In this report we provide the first clinical description and photograph of infectious keratitis.
A 41 year-old man presented with a three day history of left eye pain. He was found to have a corneal ring ulcer and infiltrate from which was cultured. The patient was successfully treated with intensive topical gatifloxacin (0.5%) and fortified tobramycin (1.5%); oral doxycycline was added to reduce corneal thinning. The patient's infection resolved with a residual scar and final best corrected visual acuity of 20/200 OS.
can present as a ring-shaped infectious corneal infiltrate and ulcer. Ring infiltrates have been observed with other microorganisms, including several other gram negative bacteria and classically, acanthamoeba. Frequently presumed to be purely immunologic, corneal ring infiltrates can have a number of other etiologies, including infectious and toxic. There are different types of immunologic rings as well, making differentiation of corneal rings sometimes difficult for the ophthalmologic generalist and subspecialist alike. In this paper we discuss characteristics of various corneal ring infiltrates, along with their immune pathophysiology. Infectious rings are distinguished from immunologic Wessely rings.
是一种罕见病原体。由该生物体引起的角膜炎从未有过专门报道或描述。在本报告中,我们提供了首例感染性角膜炎的临床描述和照片。
一名41岁男性出现左眼疼痛3天病史。发现他有角膜环形溃疡和浸润灶,从中培养出了[病原体名称未明确给出]。患者通过强化局部使用加替沙星(0.5%)和强化妥布霉素(1.5%)成功治疗;加用口服多西环素以减轻角膜变薄。患者感染消退,遗留瘢痕,最终最佳矫正视力为20/200(左眼)。
[病原体名称未明确给出]可表现为环形感染性角膜浸润和溃疡。已观察到其他微生物也可出现环形浸润,包括其他几种革兰氏阴性菌,经典的如棘阿米巴。角膜环形浸润常被认为纯粹是免疫性的,但也可能有许多其他病因,包括感染性和中毒性。也有不同类型的免疫性环,这使得眼科全科医生和专科医生有时都难以区分角膜环。在本文中,我们讨论了各种角膜环形浸润的特征及其免疫病理生理学。感染性环与免疫性韦塞利环相鉴别。