Emre Arif, Sertkaya Mehmet, Kale İlhami Taner
Department of General Surgery, Kahramanmaraş Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey.
Turk J Surg. 2017 Dec 1;33(4):274-278. doi: 10.5152/turkjsurg.2017.3582. eCollection 2017.
Appendiceal mucinous tumors can be encountered in four different types. The clinical approach varies according to these types and the severity of the present disease. We aimed to share clinical, radiological, and pathological features and surgical options of the patients diagnosed with mucinous tumors at our center.
Between August 2009 and March 2016, 757 patients underwent appendectomy for presumed diagnosis of acute appendicitis at the Department of Surgery, Kahramanmaraş Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey. Among them, demographic, clinical, and histopathological characteristics of patients who diagnosed with appendiceal mucinous tumors were retrospectively analyzed. This study was approved by our faculty's human ethics committee.
Incidence of mucinous tumor was 1.71%. Mean age of a total of 13 cases including 6 women and 7 men was 52.4±21.6 years (Range: 25-83 years). On preoperative diagnosis, acute appendicitis was detected in 8 patients, perforated appendicitis and periappendiceal abscess in two patients, and suspicious cecal mass in two patients. One patient had an operation for uterine leiomyoma. On histopathological examination, four patients were diagnosed with simple mucinous cyst, four with mucinous cystadenoma, three with mucosal hyperplasia, and two with mucinous cystadenocarcinoma. Mean duration of hospital stay was 5.1±4.7 days. One patient died from septic shock on first day, one from respiratory failure on 14th day, and one from cardiac arrest on 20th day. The average follow-up duration for the other 10 patients was 44 months (ranging from 1 to 78 months). No recurrence or death occurred in these patients over the course of follow-up.
Intraoperative clinical diagnosis of appendiceal mucinous tumors is rarely seen. Close histopathological and cytological examination of the specimen is required to separate malignant tumors from benign ones. The treatment varies depending on different types and the severity of the disease.
阑尾黏液性肿瘤有四种不同类型。临床处理方法因这些类型以及当前疾病的严重程度而异。我们旨在分享在我们中心被诊断为黏液性肿瘤患者的临床、放射学和病理学特征以及手术选择。
2009年8月至2016年3月期间，土耳其卡赫拉曼马拉什苏特西伊玛姆大学医学院外科有757例患者因疑似急性阑尾炎接受了阑尾切除术。其中，对被诊断为阑尾黏液性肿瘤患者的人口统计学、临床和组织病理学特征进行了回顾性分析。本研究获得了我们学院人类伦理委员会的批准。
黏液性肿瘤的发生率为1.71%。13例患者（6例女性和7例男性）的平均年龄为52.4±21.6岁（范围：25 - 83岁）。术前诊断时，8例患者被检测出患有急性阑尾炎，2例患者患有穿孔性阑尾炎和阑尾周围脓肿，2例患者有可疑的盲肠肿块。1例患者因子宫平滑肌瘤接受了手术。组织病理学检查显示，4例患者被诊断为单纯黏液囊肿，4例为黏液性囊腺瘤，3例为黏膜增生，2例为黏液性囊腺癌。平均住院时间为5.1±4.7天。1例患者在第一天死于感染性休克，1例在第14天死于呼吸衰竭，1例在第20天死于心脏骤停。其他10例患者的平均随访时间为44个月（范围为1至78个月）。在随访过程中，这些患者未出现复发或死亡情况。
阑尾黏液性肿瘤的术中临床诊断很少见。需要对标本进行仔细的组织病理学和细胞学检查，以区分恶性肿瘤和良性肿瘤。治疗方法因不同类型和疾病严重程度而异。
