a Academic Radiology , The University of Sheffield , Sheffield , UK.
b Sheffield Pulmonary Vascular Disease Unit , Sheffield Teaching Hospitals , Sheffield , UK.
Expert Rev Respir Med. 2018 Feb;12(2):145-160. doi: 10.1080/17476348.2018.1420478.
Pulmonary hypertension (PH) is a challenging condition to diagnose and treat. Over the last two decades, there have been significant advances in therapeutic approaches and imaging technologies. Current guidelines emphasize the importance of cardiac catheterization; however, the increasing availability of non-invasive imaging has the potential to improve diagnostic rates, whilst providing additional information on patient phenotypes. Areas covered: This review discusses the role of imaging in the diagnosis, prognostic assessment and follow-up of patients with PH. Imaging methods, ranging from established investigations (chest radiography, echocardiography, nuclear medicine and computerized tomography (CT)), to emerging modalities (dual energy CT, magnetic resonance imaging (MRI), optical coherence tomography and positron emission tomography (PET)) are reviewed. The value and limitations of the clinical utility of these imaging modalities and their potential clinical application are reviewed. Expert commentary: Imaging plays a key role in the diagnosis and classification of pulmonary hypertension. It also provides valuable prognostic information and emerging evidence supports a role for serial assessments. The authors anticipate an increasing role for imaging in the pulmonary hypertension clinic. This will reduce the need for invasive investigations, whilst providing valuable insights that will improve our understanding of disease facilitate a more targeted approach to treatment.
肺动脉高压(PH)的诊断和治疗具有挑战性。在过去的二十年中,治疗方法和成像技术取得了重大进展。目前的指南强调了心导管检查的重要性;然而,越来越多的非侵入性成像技术有可能提高诊断率,并提供有关患者表型的更多信息。
本文讨论了成像在 PH 患者的诊断、预后评估和随访中的作用。讨论了从传统的检查方法(胸部 X 线摄影、超声心动图、核医学和计算机断层扫描(CT))到新兴的方法(双能 CT、磁共振成像(MRI)、光学相干断层扫描和正电子发射断层扫描(PET))的成像方法。回顾了这些成像方式的临床应用价值和局限性及其潜在的临床应用。
成像在肺动脉高压的诊断和分类中起着关键作用。它还提供了有价值的预后信息,并且有新的证据支持对其进行连续评估。作者预计成像在肺动脉高压临床中的作用将增加。这将减少对有创性检查的需求,同时提供有价值的见解,从而加深我们对疾病的理解,促进更有针对性的治疗方法。