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Thulium laser treatment for bladder cancer.铥激光治疗膀胱癌。
Asian J Urol. 2016 Jul;3(3):130-133. doi: 10.1016/j.ajur.2016.05.002. Epub 2016 May 25.
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En bloc resection of urothelium carcinoma of the bladder (EBRUC): a European multicenter study to compare safety, efficacy, and outcome of laser and electrical en bloc transurethral resection of bladder tumor.膀胱尿路上皮癌整块切除术(EBRUC):一项欧洲多中心研究,比较激光和电切整块经尿道膀胱肿瘤切除术的安全性、有效性和结果。
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引用本文的文献

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Thulium laser en bloc resection is a safe and efficacious alternative to conventional bipolar transurethral resection of bladder tumors.铥激光整块切除是膀胱肿瘤传统双极经尿道切除术的一种安全有效的替代方法。
Cent European J Urol. 2024;77(3):466-471. doi: 10.5173/ceju.2024.103.R1. Epub 2024 Oct 28.
2
Optimal energy source selection strategies for en bloc resection in non-muscle invasive bladder cancer: a systematic review and network meta-analysis.非肌层浸润性膀胱癌整块切除的最佳能量源选择策略:一项系统评价和网状荟萃分析
World J Urol. 2025 Mar 10;43(1):155. doi: 10.1007/s00345-025-05513-8.
3
Long-term effect of transurethral partial cystectomy with a 2-micrometer continuous-wave laser for non-muscle-invasive bladder cancer.经尿道2微米连续波激光膀胱部分切除术治疗非肌层浸润性膀胱癌的长期疗效
Front Surg. 2023 Apr 17;10:1117997. doi: 10.3389/fsurg.2023.1117997. eCollection 2023.
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The Efficacy and Safety of Transurethral 2 μm Laser Bladder Lesion Mucosal En Bloc Resection in the Treatment of Cystitis Glandularis.经尿道2微米激光整块切除膀胱腺性膀胱炎黏膜病变的疗效及安全性
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Overnight Continuous Saline Bladder Irrigation After Resection of Bladder Tumor Does Not Improve Oncological Outcomes in Patients Who Have Received Intravesical Chemotherapy.膀胱肿瘤切除术后行夜间持续膀胱盐水冲洗对接受膀胱内化疗的患者的肿瘤学结局无改善作用。
Front Oncol. 2021 Mar 10;11:638065. doi: 10.3389/fonc.2021.638065. eCollection 2021.
6
Technical developments in transurethral resection of bladder tumours.经尿道膀胱肿瘤切除术的技术进展
Contemp Oncol (Pozn). 2019;23(4):195-201. doi: 10.5114/wo.2019.91530. Epub 2019 Dec 30.
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Recent advances in oncological endourology.肿瘤腔内泌尿外科的最新进展。
Asian J Urol. 2016 Jul;3(3):113-114. doi: 10.1016/j.ajur.2016.05.005. Epub 2016 Jun 4.

本文引用的文献

1
Two Micrometer Continuous-Wave Thulium Laser Treating Primary Non-Muscle-Invasive Bladder Cancer: Is It Feasible? A Randomized Prospective Study.两微米连续波铥激光治疗原发性非肌层浸润性膀胱癌:可行吗?一项随机前瞻性研究。
Photomed Laser Surg. 2015 Oct;33(10):517-23. doi: 10.1089/pho.2015.3913. Epub 2015 Sep 23.
2
The role of lasers in modern urology.激光在现代泌尿外科中的作用。
Cent European J Urol. 2015;68(2):175-82. doi: 10.5173/ceju.2015.537. Epub 2015 Jun 18.
3
Thulium Laser Endoscopic En Bloc Enucleation of Nonmuscle-Invasive Bladder Cancer.铥激光内镜整块剜除非肌层浸润性膀胱癌
J Endourol. 2015 Nov;29(11):1258-62. doi: 10.1089/end.2015.0336. Epub 2015 Aug 3.
4
En bloc resection of urothelium carcinoma of the bladder (EBRUC): a European multicenter study to compare safety, efficacy, and outcome of laser and electrical en bloc transurethral resection of bladder tumor.膀胱尿路上皮癌整块切除术(EBRUC):一项欧洲多中心研究,比较激光和电切整块经尿道膀胱肿瘤切除术的安全性、有效性和结果。
World J Urol. 2015 Dec;33(12):1937-43. doi: 10.1007/s00345-015-1568-6. Epub 2015 Apr 25.
5
Safety and efficacy of transurethral laser therapy for bladder cancer: a systematic review and meta-analysis.经尿道激光治疗膀胱癌的安全性和有效性:一项系统评价和荟萃分析。
World J Surg Oncol. 2014 Sep 25;12:301. doi: 10.1186/1477-7819-12-301.
6
En bloc transurethral resection with 2-micron continuous-wave laser for primary non-muscle-invasive bladder cancer: a randomized controlled trial.2微米连续波激光整块经尿道切除术治疗原发性非肌层浸润性膀胱癌:一项随机对照试验
World J Urol. 2015 Jul;33(7):989-95. doi: 10.1007/s00345-014-1342-1. Epub 2014 Jun 21.
7
Current evidence of transurethral Ho:YAG and Tm:YAG treatment of bladder cancer: update 2014.经尿道钬激光和铥激光治疗膀胱癌的当前证据:2014年更新
World J Urol. 2015 Apr;33(4):571-9. doi: 10.1007/s00345-014-1337-y. Epub 2014 Jun 17.
8
EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013.EAU 指南:非肌层浸润性膀胱尿路上皮癌:2013 年更新版。
Eur Urol. 2013 Oct;64(4):639-53. doi: 10.1016/j.eururo.2013.06.003. Epub 2013 Jun 12.
9
Comparison of the safety and efficacy of conventional monopolar and 2-micron laser transurethral resection in the management of multiple nonmuscle-invasive bladder cancer.传统单极与2微米激光经尿道切除术治疗多发性非肌层浸润性膀胱癌的安全性和疗效比较。
J Int Med Res. 2013 Aug;41(4):984-92. doi: 10.1177/0300060513477001. Epub 2013 Jun 12.
10
Older patients suffer from adverse histopathological features after radical cystectomy.老年患者在根治性膀胱切除术后会出现不良的组织病理学特征。
Int J Urol. 2011 Aug;18(8):576-84. doi: 10.1111/j.1442-2042.2011.02794.x. Epub 2011 Jun 23.

铥激光治疗膀胱癌。

Thulium laser treatment for bladder cancer.

作者信息

Wang Wei, Liu Haitao, Xia Shujie

机构信息

Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Asian J Urol. 2016 Jul;3(3):130-133. doi: 10.1016/j.ajur.2016.05.002. Epub 2016 May 25.

DOI:10.1016/j.ajur.2016.05.002
PMID:29264180
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5730823/
Abstract

Recent innovations in thulium laser techniques have allowed application in the treatment of bladder cancer. Laser en bloc resection of bladder cancer is a transurethral procedure that may offer an alternative to the conventional transurethral resection procedure. We conducted a review of basic thulium laser physics and laser en bloc resection procedures and summarized the current clinical literature with a focus on complications and outcomes. Literature evidence suggests that thulium laser techniques including smooth incision, tissue vaporization, and en bloc resection represent feasible, safe, and effective procedures in the treatment of bladder cancer. Moreover, these techniques allow improved specimen orientation and accurate determination of invasion depth, facilitating correct diagnosis, restaging, and re-evaluation of the need for a second resection. Nonetheless, large-scale multicentre studies with longer follow-up are warranted for a robust assessment. The present review is meant as a quick reference for urologists.

摘要

近年来,铥激光技术的创新使其可应用于膀胱癌的治疗。膀胱癌整块激光切除术是一种经尿道手术,可能为传统经尿道切除术提供替代方案。我们回顾了铥激光的基本物理原理和整块激光切除手术,并总结了当前的临床文献,重点关注并发症和治疗结果。文献证据表明,铥激光技术,包括平滑切割、组织汽化和整块切除,是治疗膀胱癌可行、安全且有效的方法。此外,这些技术有助于改善标本定位并准确确定浸润深度,便于进行正确的诊断、重新分期以及重新评估是否需要二次切除。尽管如此,仍需要开展大规模、多中心且随访时间更长的研究,以进行全面评估。本综述旨在为泌尿外科医生提供快速参考。