缺血性脑损伤在致命性非贯通性颅脑损伤中仍很常见。
Ischaemic brain damage is still common in fatal non-missile head injury.
作者信息
Graham D I, Ford I, Adams J H, Doyle D, Teasdale G M, Lawrence A E, McLellan D R
机构信息
Department of Neuropathology, University of Glasgow, Scotland, UK.
出版信息
J Neurol Neurosurg Psychiatry. 1989 Mar;52(3):346-50. doi: 10.1136/jnnp.52.3.346.
A detailed neuropathological examination has been undertaken on a consecutive series of head injuries dying in the Institute of Neurological Sciences, Glasgow, between 1968-72 (151 cases) and 1981-82 (112 cases) in order to determine the frequency and distribution of any ischaemic brain damage. Ischaemic damage was found in the brains of 92% of the 1968-72 cases and in 88% of the 1981-82 cases: there was no statistical difference in the amount of moderately severe and severe ischaemic damage in the two groups, 55% and 54% respectively. There was evidence, however, that an increased number of patients with severe ischaemic brain damage was admitted in 1981-82 as a result of a changed admission policy of the Department of Neurosurgery that resulted in an increased detection of intracranial haematomas. It is concluded that ischaemic brain damage is still common after severe head injury, and it seems likely that it remains an important cause of mortality and morbidity.
为了确定缺血性脑损伤的发生频率和分布情况，对1968年至1972年间（151例）以及1981年至1982年间（112例）在格拉斯哥神经科学研究所死亡的一系列连续性头部损伤病例进行了详细的神经病理学检查。在1968年至1972年的病例中，92%的患者大脑出现了缺血性损伤；在1981年至1982年的病例中，这一比例为88%。两组中中度严重和严重缺血性损伤的数量没有统计学差异，分别为55%和54%。然而，有证据表明，由于神经外科部门入院政策的改变导致颅内血肿检出率增加，1981年至1982年期间收治的严重缺血性脑损伤患者数量有所增加。研究得出结论，严重头部损伤后缺血性脑损伤仍然很常见，而且它似乎仍然是死亡和发病的重要原因。
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