一名10岁儿童的大疱性系统性红斑狼疮。

Bullous systemic lupus erythematosus in a 10-year-old child.

作者信息

Hans-Bittner Nelise Ritter, Bittner Guilherme Canho, Hans Günter, Takita Luiz Carlos

机构信息

Dr. Günter Hans Department of Dermatology at Hospital Universitário Maria Aparecida Pedrossian, of the Universidade Federal de Mato Grosso do Sul (HUMAP-UFMS) - Campo Grande (MS), Brazil.

Discipline of Dermatology of the Faculdade de Medicina, Universidade Federal de Mato Grosso do Sul (FAMED-UFMS) - Campo Grande (MS), Brazil.

出版信息

An Bras Dermatol. 2017;92(5 Suppl 1):37-39. doi: 10.1590/abd1806-4841.20176074.

DOI:10.1590/abd1806-4841.20176074

PMID:29267441

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5726672/

Abstract

Bullous systemic lupus erythematosus (BSLE) is a rare autoimmune subepidermal blistering disease, with few cases described in childhood. It has different clinical-pathological features. We report a case of BSLE in a 10-year-old child with systemic lupus erythematosus, treated with prednisone and hydroxychloroquine. There was complete remission with dapsone, with no recurrence of skin lesions throughout one year of follow-up. We highlight the rarity and early age of occurrence.

摘要

大疱性系统性红斑狼疮（BSLE）是一种罕见的自身免疫性表皮下大疱性疾病，儿童病例报道较少。它具有不同的临床病理特征。我们报告一例10岁患有系统性红斑狼疮的儿童BSLE病例，采用泼尼松和羟氯喹治疗。使用氨苯砜后完全缓解，在一年的随访中皮肤病变未复发。我们强调了其罕见性和发病年龄早的特点。