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The role of Piccolo in cancer treatment: relationship with EGFR and related therapies, and a marker for new targeted therapies.

作者信息

Frattini Milo, Molinari Francesca, Epistolio Samantha

机构信息

Laboratory of Molecular Pathology, Institute of Pathology, Locarno, Switzerland.

出版信息

J Thorac Dis. 2017 Nov;9(11):4240-4243. doi: 10.21037/jtd.2017.10.38.

DOI:10.21037/jtd.2017.10.38
PMID:29268482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5721053/
Abstract
摘要

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Oncologist. 2017 Jul;22(7):782-e70. doi: 10.1634/theoncologist.2017-0069. Epub 2017 Jun 7.
2
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Oncogene. 2017 Jul 6;36(27):3890-3902. doi: 10.1038/onc.2017.15. Epub 2017 Mar 6.
3
Cancer Statistics, 2017.《2017 年癌症统计》
CA Cancer J Clin. 2017 Jan;67(1):7-30. doi: 10.3322/caac.21387. Epub 2017 Jan 5.
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Spectrum of Gene Mutations in Colorectal Cancer: Implications for Treatment.结直肠癌中的基因突变谱:对治疗的意义
Cancer J. 2016 May-Jun;22(3):149-55. doi: 10.1097/PPO.0000000000000191.
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Bassoon and piccolo regulate ubiquitination and link presynaptic molecular dynamics with activity-regulated gene expression.巴松管蛋白和短笛蛋白调节泛素化,并将突触前分子动力学与活性调节基因表达联系起来。
J Physiol. 2016 Oct 1;594(19):5441-8. doi: 10.1113/JP271826. Epub 2016 Apr 24.
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NEU3 activity enhances EGFR activation without affecting EGFR expression and acts on its sialylation levels.NEU3活性增强表皮生长因子受体(EGFR)的激活,而不影响EGFR的表达,并作用于其唾液酸化水平。
Glycobiology. 2015 Aug;25(8):855-68. doi: 10.1093/glycob/cwv026. Epub 2015 Apr 28.
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A panel of overexpressed proteins for prognosis in esophageal squamous cell carcinoma.用于食管鳞状细胞癌预后的一组过表达蛋白。
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