Brigham and Women's Hospital, Department of Pathology, Division of Women's and Perinatal Pathology, Boston, MA, USA; Department of Pathology, Stanford School of Medicine, Stanford, CA, United States.
Brigham and Women's Hospital, Department of Pathology, Division of Women's and Perinatal Pathology, Boston, MA, USA.
Pathology. 2018 Feb;50(2):141-150. doi: 10.1016/j.pathol.2017.11.084. Epub 2017 Dec 19.
The mesonephric (Wolffian) duct regresses in females during embryological development. Remnants of this duct may persist typically along the lateral walls of the cervix, vagina, adnexa, and uterine corpus. These mesonephric epithelia may expand into hyperplastic proliferations and rarely form neoplasms. The spectrum of morphology, immunophenotype, clinical presentation, and molecular characteristics of mesonephric lesions is reviewed, with attention to distinction from entities in the differential diagnosis.
中肾管（沃夫管）在女性胚胎发育过程中退化。该导管的残余物通常沿着宫颈、阴道、附件和子宫体的侧壁持续存在。这些中肾管上皮可能会扩张成增生性增殖，并很少形成肿瘤。本文复习了中肾管病变的形态学、免疫表型、临床表现和分子特征谱，重点关注与鉴别诊断中不同实体的区别。
