• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Naturally occurring genotypic drug-resistant mutations of HBV in Huzhou, China: a single-center study.中国湖州自然发生的乙型肝炎病毒基因型耐药突变：一项单中心研究。
Infect Drug Resist. 2017 Dec 14;10:507-509. doi: 10.2147/IDR.S149992. eCollection 2017.
2
Monitoring of genotypic resistance profile in chronic hepatitis B patients receiving nucleos(t)ide analogues in Huzhou, China.中国湖州接受核苷（酸）类似物治疗的慢性乙型肝炎患者的基因型耐药谱监测。
J Infect Dev Ctries. 2016 Sep 30;10(9):996-1002. doi: 10.3855/jidc.8020.
3
Tenofovir is a more suitable treatment than entecavir for chronic hepatitis B patients carrying naturally occurring rtM204I mutations.替诺福韦相对于恩替卡韦更适合治疗携带天然 rtM204I 突变的慢性乙型肝炎患者。
World J Gastroenterol. 2019 Sep 7;25(33):4985-4998. doi: 10.3748/wjg.v25.i33.4985.
4
Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China.中国北方大量B基因型和C基因型乙型肝炎病毒感染患者耐药突变的检出率及突变模式比较
Microb Drug Resist. 2017 Jun;23(4):516-522. doi: 10.1089/mdr.2016.0093. Epub 2016 Oct 28.
5
Profile of HBV antiviral resistance mutations with distinct evolutionary pathways against nucleoside/nucleotide analogue treatment among Chinese chronic hepatitis B patients.中国慢性乙型肝炎患者中针对核苷/核苷酸类似物治疗具有不同进化途径的HBV抗病毒耐药突变特征
Antivir Ther. 2010;15(8):1171-8. doi: 10.3851/IMP1677.
6
Naturally occurring antiviral drug resistance in HIV patients who are mono-infected or co-infected with HBV or HCV in China.中国单感染或合并感染 HBV 或 HCV 的 HIV 患者中自然发生的抗病毒药物耐药性。
J Med Virol. 2018 Jul;90(7):1246-1256. doi: 10.1002/jmv.25078. Epub 2018 Mar 31.
7
High Prevalence of HBV Lamivudine-Resistant Mutations in HBV/HIV Co-Infected Patients on Antiretroviral Therapy in the Area with the Highest Prevalence of HIV/HBV Co-Infection in China.中国 HIV 和 HBV 合并感染发生率最高的地区，在接受抗逆转录病毒治疗的 HIV/HBV 合并感染患者中，HBV 拉米夫定耐药突变的发生率很高。
Intervirology. 2018;61(3):123-132. doi: 10.1159/000493797. Epub 2018 Oct 26.
8
Naturally occurring core protein mutations compensate for the reduced replication fitness of a lamivudine-resistant HBV isolate.天然发生的核心蛋白突变补偿了拉米夫定耐药 HBV 分离株的复制适应性降低。
Antiviral Res. 2019 May;165:47-54. doi: 10.1016/j.antiviral.2019.03.006. Epub 2019 Mar 19.
9
Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection.对845例初治慢性乙型肝炎病毒（HBV）感染中国患者的HBV耐药突变进行调查。
Antivir Ther. 2015;20(2):141-7. doi: 10.3851/IMP2813. Epub 2014 Jul 3.
10
[Complete Genome Analysis of a Recombinant GI Norovirus Identified in Huzhou,China].[中国湖州分离的一株重组GⅠ型诺如病毒的全基因组分析]
Bing Du Xue Bao. 2016 May;32(3):263-6.

引用本文的文献

1
Mutational characterization of HBV reverse transcriptase gene and the genotype-phenotype correlation of antiviral resistance among Chinese chronic hepatitis B patients.HBV 逆转录酶基因的突变特征及中国慢性乙型肝炎患者抗病毒耐药的基因型-表型相关性。
Emerg Microbes Infect. 2020 Dec;9(1):2381-2393. doi: 10.1080/22221751.2020.1835446.
2
Characterization and Clinical Significance of Natural Variability in Hepatitis B Virus Reverse Transcriptase in Treatment-Naive Chinese Patients by Sanger Sequencing and Next-Generation Sequencing.采用 Sanger 测序和下一代测序对未经治疗的中国患者乙型肝炎病毒逆转录酶的自然变异性进行鉴定和临床意义分析。
J Clin Microbiol. 2019 Jul 26;57(8). doi: 10.1128/JCM.00119-19. Print 2019 Aug.
3
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression.天然发生的乙型肝炎病毒逆转录酶突变与潜在的抗病毒药物耐药性和肝病进展有关。
World J Gastroenterol. 2018 Apr 28;24(16):1708-1724. doi: 10.3748/wjg.v24.i16.1708.

本文引用的文献

1
Monitoring of genotypic resistance profile in chronic hepatitis B patients receiving nucleos(t)ide analogues in Huzhou, China.中国湖州接受核苷（酸）类似物治疗的慢性乙型肝炎患者的基因型耐药谱监测。
J Infect Dev Ctries. 2016 Sep 30;10(9):996-1002. doi: 10.3855/jidc.8020.
2
Prevalence of mutations in HBV DNA polymerase gene associated with nucleos(t)ide resistance in treatment-naive patients with Chronic Hepatitis B in Central China.中国中部初治慢性乙型肝炎患者中与核苷（酸）类耐药相关的乙肝病毒DNA聚合酶基因突变的流行情况
Braz J Infect Dis. 2016 Mar-Apr;20(2):173-8. doi: 10.1016/j.bjid.2015.12.006. Epub 2016 Feb 12.
3
An epidemiological serosurvey of hepatitis B virus shows evidence of declining prevalence due to hepatitis B vaccination in central China.一项关于乙型肝炎病毒的流行病学血清学调查显示，由于在中国中部地区进行了乙肝疫苗接种，其流行率有下降的迹象。
Int J Infect Dis. 2015 Nov;40:75-80. doi: 10.1016/j.ijid.2015.10.002. Epub 2015 Oct 9.
4
Pre-existing mutations in reverse transcriptase of hepatitis B virus in treatment-naive Chinese patients with chronic hepatitis B.未经治疗的中国慢性乙型肝炎患者中乙型肝炎病毒逆转录酶的预存突变
PLoS One. 2015 Mar 30;10(3):e0117429. doi: 10.1371/journal.pone.0117429. eCollection 2015.
5
Incidence of natural resistance mutations in naïve chronic hepatitis B patients: a systematic review and meta-analysis.初治慢性乙型肝炎患者自然耐药突变的发生率：一项系统评价和荟萃分析
J Gastroenterol Hepatol. 2015 Feb;30(2):252-61. doi: 10.1111/jgh.12831.
6
Investigation into drug-resistant mutations of HBV from 845 nucleoside/nucleotide analogue-naive Chinese patients with chronic HBV infection.对845例初治慢性乙型肝炎病毒（HBV）感染中国患者的HBV耐药突变进行调查。
Antivir Ther. 2015;20(2):141-7. doi: 10.3851/IMP2813. Epub 2014 Jul 3.
7
Genotype-specific mutations in the polymerase gene of hepatitis B virus potentially associated with resistance to oral antiviral therapy.乙型肝炎病毒聚合酶基因的基因型特异性突变与口服抗病毒治疗耐药相关。
Antiviral Res. 2012 Dec;96(3):422-9. doi: 10.1016/j.antiviral.2012.09.014. Epub 2012 Sep 28.

Naturally occurring genotypic drug-resistant mutations of HBV in Huzhou, China: a single-center study.

作者信息

Qian Fuchu, Zou Weihua, Qin Jiqu, Li Dongli

机构信息

Huzhou Key Laboratory of Molecular Medicine.

Department of Laboratory Medicine, Huzhou Central Hospital, Huzhou, China.

出版信息

Infect Drug Resist. 2017 Dec 14;10:507-509. doi: 10.2147/IDR.S149992. eCollection 2017.

DOI:10.2147/IDR.S149992
PMID:29276396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5733919/
Abstract
摘要