Shanghai Dermatology Hospital Department of photomedicine, The Institute of Photomedicine Tongji University School of Medicine, Shanghai, China.
Shanghai Dermatology Hospital Department of photomedicine, The Institute of Photomedicine Tongji University School of Medicine, Shanghai, China.
Photodiagnosis Photodyn Ther. 2018 Mar;21:393-395. doi: 10.1016/j.pdpdt.2017.12.010. Epub 2017 Dec 19.
Giant cutaneous squamous cell carcinoma (cSCC) in elderly people is difficult to treat. Herein, we report a case of 96-year-old male who was diagnosed to have giant facial invasive SCC (4cm4.5cm2 cm). He was successfully treated with plum-blossom needle assisted photodynamic therapy (PDT) sequential with imiquimod. The patient achieved complete remission after 9 sessions of PDT and 3 months of imiquimod but developed residual vitiligo-like hypopigmentation. There was no recurrence at 18 months of follow-up. This case suggests that plum-blossom needle pretreated PDT sequential by topical imiquimod is a viable treatment option for refractory and giant thick SCC.
老年人的巨大皮肤鳞状细胞癌（cSCC）难以治疗。在此，我们报告一例 96 岁男性患者，诊断为巨大面部侵袭性 SCC（4cm4.5cm2cm）。他成功地接受了梅花针辅助光动力疗法（PDT）联合咪喹莫特治疗。患者在接受 9 次 PDT 和 3 个月咪喹莫特治疗后完全缓解，但出现残余的白癜风样色素减退。随访 18 个月无复发。该病例提示，梅花针预处理 PDT 联合局部咪喹莫特是治疗难治性和巨大厚 SCC 的一种可行选择。
