Department of Oral Medicine, Peking University School and Hospital of Stomatology, Beijing 100081, PR China.
Department of Oral Medicine, Peking University School and Hospital of Stomatology, Beijing 100081, PR China.
Photodiagnosis Photodyn Ther. 2019 Mar;25:296-299. doi: 10.1016/j.pdpdt.2019.01.011. Epub 2019 Jan 8.
Oral leukoplakia (OLK) is one of the most common oral potentially-malignant disorders (OPMD) with complex causes, a long disease course and a high tendency for recrudescence. Although a variety of methods exist for treating this disease, canceration rates remain high. Herein, we described a case of 72-year-old male patient with OLK of the palatine mucous membrane who had achieved complete remission after being treated with five sessions of plum-blossom needle (PBN) assisted 5-aminolevulinic acid-photodynamic therapy (ALA-PDT). The patient had since been subsequently placed under close observation (>12 mo). To date, there has been no recurrence. PBN assisted PDT might be suitable for the treatment of OPMDs in patients presenting with epithelial hyperkeratosis.
口腔白斑病（OLK）是最常见的口腔潜在恶性疾病（OPMD）之一，其病因复杂，病程长，复发率高。尽管有多种方法可用于治疗这种疾病，但癌变率仍然很高。在此，我们描述了 1 例 72 岁男性腭黏膜 OLK 患者，经 5 次梅花针（PBN）辅助 5-氨基酮戊酸-光动力疗法（ALA-PDT）治疗后获得完全缓解。此后，患者一直密切观察（>12 个月）。到目前为止，没有复发。PBN 辅助 PDT 可能适合治疗上皮过度角化的 OPMD 患者。
