Psychological Sciences, University of Liverpool, Waterhouse Building, Block B, 2nd Floor, L69 3BX, United Kingdom.
School of Health Sciences, Thompson Yates Building, The Quadrangle, Brownlow Hill, Liverpool L69 3GB, United Kingdom.
Neuropsychologia. 2018 Mar;111:16-25. doi: 10.1016/j.neuropsychologia.2017.12.035. Epub 2017 Dec 23.
Distinguishing the effects of own from others' actions is a prerequisite for effective interpersonal functioning. Individuals differ in their ability to do this. For example, difficulties in self-other attribution have been linked to positive symptoms of schizophrenia such as hallucinations, with causally ambiguous situations proving a universal challenge. The goal of the present study was to examine relationships between individual differences in resting-state functional connectivity and self-other attribution performance. Fifty-five healthy adults completed a resting-state fMRI scan and an attribution task that involved tapping at irregular intervals while listening to a tone sequence. The likelihood that tones in the sequence corresponded to the participant's taps was systematically varied. Using group independent component analysis (ICA) and dual regression, we found that connectivity between prefrontal networks associated with self-referential processing and regions sensitive to externally-generated stimuli was modulated by participants' ability to accurately assess the proportion of tones belonging to self versus other. These findings shed additional light on the neural mechanisms of agency, emphasising that connectivity with prefrontal networks play an important role in self-other differentiation.
区分自己和他人行为的影响是有效人际互动的前提。个体在完成这种区分的能力上存在差异。例如，自我归因困难与精神分裂症的阳性症状（如幻觉）有关，因果关系不明确的情况被证明是一个普遍的挑战。本研究的目的是检验静息态功能连接个体差异与自我归因表现之间的关系。55 名健康成年人完成了静息态 fMRI 扫描和归因任务，在听一段音调序列的同时，以不规则的间隔进行敲击。序列中的音调与参与者敲击的对应概率被系统地改变。使用组独立成分分析（ICA）和双回归，我们发现与自我参照处理相关的前额叶网络与对外界刺激敏感的区域之间的连接受到参与者准确评估属于自我和他人的音调比例的能力的调节。这些发现进一步揭示了代理的神经机制，强调与前额叶网络的连接在自我与他人的区分中起着重要作用。
