Department of Psychology, Zhejiang Normal University, Jinhua, Zhejiang Province, PR China; Institute of Psychological and Brain Sciences, Zhejiang Normal University, Jinhua, Zhejiang Province, PR China.
Department of Psychology, Zhejiang Normal University, Jinhua, Zhejiang Province, PR China.
Int J Psychophysiol. 2018 Jun;128:31-39. doi: 10.1016/j.ijpsycho.2018.03.014. Epub 2018 Mar 21.
In this study, we investigated neural responses during resting-state and reward-task-based fMRI and how these related to individual differences in self-reported reward sensitivity. Resting-state fMRI data were collected from 191 college students, and 60 of these individuals further finished a reward-related fMRI task. Self-reported reward-approach tendencies were assessed using the behavioral activation scale. Behavioral activation scale scores were positively correlated with brain activations in the striatum bilaterally during reward processing. During rest, behavioral activation scale scores were positively correlated with functional connectivity between the left and right striatum and with functional connectivity between the right striatum and right middle frontal gyrus. Positive correlations were found between task-based striatal activations and the functional connectivity between the left and right striatum at rest. These results suggest a relationship between striatal task-based reward-related activations and resting connectivity strengths that relate to individual differences in reward-approach tendencies.
在这项研究中，我们调查了静息态和基于奖励任务的 fMRI 期间的神经反应，以及这些反应与个体报告的奖励敏感性差异的关系。从 191 名大学生中收集了静息态 fMRI 数据，其中 60 人进一步完成了与奖励相关的 fMRI 任务。使用行为激活量表评估个体报告的奖励趋近倾向。在奖励处理过程中，行为激活量表评分与双侧纹状体的大脑激活呈正相关。在静息状态下，行为激活量表评分与左侧和右侧纹状体之间的功能连接以及右侧纹状体和右侧额中回之间的功能连接呈正相关。基于任务的纹状体激活与静息状态下左侧和右侧纹状体之间的功能连接之间存在正相关。这些结果表明，纹状体基于任务的奖励相关激活与静息状态连接强度之间存在关系，这种关系与奖励趋近倾向的个体差异有关。
