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预防艾滋病病毒传播的策略:一种积极主动的方法。

Prevention Strategies Against HIV Transmission: A Proactive Approach.

作者信息

Carrion Antonio J, Miles Jovan D, Mosley Juan F, Smith Lillian L, Prather April S, Gurley Marcus M, Phan Linh D, Everton Emily C

机构信息

1 College of Pharmacy and Pharmaceutical Sciences, Florida Agricultural and Mechanical University, Tallahassee, FL, USA.

2 College of Pharmacy and Pharmaceutical Sciences, Florida Agricultural and Mechanical University, Crestview Education Center, Crestview, FL, USA.

出版信息

J Pharm Pract. 2018 Feb;31(1):82-90. doi: 10.1177/0897190017696946. Epub 2017 Mar 21.

Abstract

Human immunodeficiency virus (HIV) has now transformed into a manageable chronic condition. Highly active antiretroviral therapy (HAART) has proven efficacious at controlling the disease progression. Based on compelling evidence, the Department of Health and Human Services (DHHS) and the Infectious Disease Society of America (IDSA) developed guidelines for the management of persons infected with HIV. However, there are approximately 50 000 new cases of HIV in the United States each year. In this article, we review proactive methods to reduce the transmission of HIV, which include reinforcing patient education, gel-coated condoms that destroy HIV, HIV vaccinations, and adequately utilizing pre-exposure prophylaxis (PrEP), and post-exposure prophylaxis (PEP). Further development and consistent utilization of innovative prevention tools can significantly reduce the incidence of HIV infections regardless of HIV status.

摘要

人类免疫缺陷病毒(HIV)现已转变为一种可控制的慢性病。高效抗逆转录病毒疗法(HAART)已被证明在控制疾病进展方面有效。基于确凿的证据,美国卫生与公众服务部(DHHS)和美国传染病学会(IDSA)制定了HIV感染者管理指南。然而,美国每年仍有大约5万例新的HIV病例。在本文中,我们回顾了减少HIV传播的积极方法,包括加强患者教育、能破坏HIV的凝胶涂层避孕套、HIV疫苗接种,以及充分利用暴露前预防(PrEP)和暴露后预防(PEP)。无论HIV感染状况如何,进一步开发和持续使用创新的预防工具都可以显著降低HIV感染的发生率。

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