Saadeh Michael, Zhao Yili, Galadima Hadiza, Chaoui Rabih, Sinkovskaya Elena, Abuhamad Alfred
Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia, USA.
Center for Health Analytics and Discovery, Eastern Virginia Medical School, Norfolk, Virginia, USA.
J Ultrasound Med. 2018 Jul;37(7):1673-1680. doi: 10.1002/jum.14515. Epub 2017 Dec 27.
The aim of this study was to compare the size and position of the cavum septi pellucidi (CSP) in fetuses with hypoplastic left heart syndrome (HLHS) or dextro-transposition of the great arteries (d-TGA) with healthy fetuses.
The CSP length, CSP width, and frontal lobe length were measured in 185 healthy fetuses (404 scans), 11 fetuses with HLHS (16 scans), and 11 fetuses with d-TGA (12 scans) between January 2005 and April 2016. Each measurement was compared between healthy fetuses and those with HLHS or d-TGA, controlling for the biparietal diameter.
Positive correlations were noted between biparietal diameter and CSP length, CSP width, and frontal lobe length (adjusted R = 0.811, 0.821, and 0.878, respectively). An increased CSP length was found in both fetuses with HLHS and those with d-TGA (P < .0001). The CSP width was only increased in fetuses with d-TGA (P = .0466). No difference in the frontal lobe length was noted.
In fetuses with HLHS, the CSP is increased in length. In fetuses with d-TGA, the CSP is increased in both length and width.
本研究旨在比较患有左心发育不全综合征（HLHS）或大动脉右位转位（d-TGA）的胎儿与健康胎儿的透明隔腔（CSP）的大小和位置。
在2005年1月至2016年4月期间，对185例健康胎儿（404次扫描）、11例患有HLHS的胎儿（16次扫描）和11例患有d-TGA的胎儿（12次扫描）测量CSP长度、CSP宽度和额叶长度。在控制双顶径的情况下，比较健康胎儿与患有HLHS或d-TGA的胎儿之间的各项测量值。
双顶径与CSP长度、CSP宽度和额叶长度之间呈正相关（调整后的R分别为0.811、0.821和0.878）。发现患有HLHS的胎儿和患有d-TGA的胎儿的CSP长度均增加（P <.0001）。仅患有d-TGA的胎儿的CSP宽度增加（P = 0.0466）。未观察到额叶长度有差异。
患有HLHS的胎儿，其CSP长度增加。患有d-TGA的胎儿，其CSP的长度和宽度均增加。
