Kayar S R, Hoppeler H, Lindstedt S L, Claassen H, Jones J H, Essen-Gustavsson B, Taylor C R
Institute of Anatomy, University of Bern, Switzerland.
Pflugers Arch. 1989 Feb;413(4):343-7. doi: 10.1007/BF00584481.
The relationship between maximal oxygen consumption rate (VO2max) and mitochondrial content of skeletal muscles was examined in horses and steers (n = 3 each). Samples of the heart left ventricle, diaphragm, m. vastus medialis, m. semitendinosus, m. cutaneous thoracicus and m. masseter, as well as samples of muscles collected in a whole-body sampling procedure, were analyzed by electron microscopy. VO2max per kilogram body mass was 2.7 x greater in horses than steers. This higher VO2max was in proportion to the higher total volume of mitochondria in horse versus steer muscle when analyzed from the whole-body samples and from the locomotor muscle samples. In non-locomotor muscles, total mitochondrial volume was greater in horses than steers, but not in proportion to their differences in VO2max. The VO2max of the mitochondria was estimated to be close to 4.5 ml O2.ml-1 mitochondria in both species. It is concluded that in a comparison of a highly aerobic to a less aerobic mammalian species of similar body size, a higher oxidative potential may be found in all muscles of the more aerobic species. This greater oxidative potential is achieved by a greater total volume of skeletal muscle mitochondria.
研究了马和公牛（每组n = 3）的最大耗氧率（VO2max）与骨骼肌线粒体含量之间的关系。通过电子显微镜分析了心脏左心室、膈肌、股内侧肌、半腱肌、胸皮肌和咬肌的样本，以及在全身采样过程中采集的肌肉样本。每千克体重的VO2max，马比公牛高2.7倍。从全身样本和运动肌肉样本分析时，马的这种较高的VO2max与马和公牛肌肉中线粒体的总体积较高成正比。在非运动肌肉中，马的线粒体总体积大于公牛，但与它们VO2max的差异不成比例。估计两种动物线粒体的VO2max接近4.5 ml O2.ml-1线粒体。结论是，在比较体型相似的高需氧型和低需氧型哺乳动物物种时，在需氧性更强的物种的所有肌肉中可能会发现更高的氧化潜力。这种更大的氧化潜力是通过骨骼肌线粒体的更大总体积实现的。
