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二尖瓣修复术后二尖瓣瓣叶对合高度与二尖瓣反流之间的相关性。

The correlation between the coaptation height of mitral valve and mitral regurgitation after mitral valve repair.

作者信息

Wei Dan, Han Jie, Zhang Haibo, Li Yan, Xu Chunlei, Meng Xu

机构信息

Department of cardiac surgery, Capital medical university affiliated Beijing anzhen hospital, Chaoyang District Anzhen Road No. 2, Beijing, 100029, China.

出版信息

J Cardiothorac Surg. 2017 Dec 28;12(1):120. doi: 10.1186/s13019-017-0687-0.

DOI:10.1186/s13019-017-0687-0
PMID:29282097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5745608/
Abstract

BACKGROUND

To investigate the association between the coaptation height of mitral valve and mitral regurgitation after mitral valve repair.

METHODS

From Sep 2014 to Jun 2015, 20 patients underwent mitral valve valvuloplasty for mitral regurgitation were included. Ring annuloplasty was performed in all cases. Mitral valve short-axis dimension (MVd), coaptation height (CH), Left ventricular ejection fraction (LVEF) were measured by the transesophageal echocardiography before the operation in operation room and 3 months and 12 months after the operation by the transthoracic echocardiography. A degree from 0 to 4 was used to measure the degree of mitral regurgitation.

RESULTS

There were 14 patients with 0, 3 patients with 1, 3 patients with 2 of mitral regurgitation 12 months after the operation. CH (3.53 ± 1.91 mm) increased significantly at 3 months (5.05 ± 1.09 mm) and 12 months after operation (5.22 ± 1.15 mm) (p < 0.05). MVd and LVEF were not significantly changed after mitral valve repair. Furthermore, CH after resuscitation have a statistically significant negative correlation with the degree of mitral regurgitation 12 months after operation.

CONCLUSION

The mitral valve repair with mitral valve ring induce the morphologic change of the mitral valve structure. The increase of CH after mitral valve repair may be one of the main factors in regulation of mitral regurgitation.

摘要

背景

探讨二尖瓣修复术后二尖瓣瓣叶对合高度与二尖瓣反流之间的关系。

方法

纳入2014年9月至2015年6月期间因二尖瓣反流接受二尖瓣成形术的20例患者。所有病例均行瓣环成形术。在手术室手术前通过经食管超声心动图测量二尖瓣短轴径(MVd)、瓣叶对合高度(CH)、左心室射血分数(LVEF),术后3个月和12个月通过经胸超声心动图测量。采用0至4级来衡量二尖瓣反流程度。

结果

术后12个月,二尖瓣反流程度为0级的患者有14例,1级的有3例,2级的有3例。CH在术后3个月(5.05±1.09mm)和12个月(5.22±1.15mm)时显著增加(p<0.05)。二尖瓣修复术后MVd和LVEF无显著变化。此外,复苏后的CH与术后12个月二尖瓣反流程度呈显著负相关。

结论

二尖瓣环二尖瓣修复术可引起二尖瓣结构的形态学改变。二尖瓣修复术后CH的增加可能是调节二尖瓣反流的主要因素之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/f12fcc2f631f/13019_2017_687_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/78d74d637009/13019_2017_687_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/abd426a393a5/13019_2017_687_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/f12fcc2f631f/13019_2017_687_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/78d74d637009/13019_2017_687_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/abd426a393a5/13019_2017_687_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fe/5745608/f12fcc2f631f/13019_2017_687_Fig3_HTML.jpg

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