Nie Boyuan, Chen Xueying, Li Jing, Wu Dou, Liu Qiang
Department of Orthopedic Surgery, Dayi Hospital of Shanxi Medical University, NO.99 Longcheng Street, Taiyuan, Shanxi, 030032, People's Republic of China.
Biological Material R&D Center, China Institute for Radiation Protection, NO.102 Xuefu Street, Taiyuan, Shanxi, 030006, People's Republic of China.
J Orthop Surg Res. 2017 Dec 28;12(1):197. doi: 10.1186/s13018-017-0673-1.
The major objective of the present study is to investigate the differences in the load and strain changes in the intertrochanteric region of human cadaveric femora between the loss of medial or lateral wall and after treatment with proximal femoral nail antirotation (PFNA).
After measuring the geometry of the proximal femur region and modeling the medial or lateral wall defect femoral models, six pairs of freshly frozen human femora were randomly assigned in the medial or lateral wall group. According to a single-leg stance model, an axial loading was applied, and the strain distribution was measured before and after PFNA implantation. The strains of each specimen were recorded at load levels of 350, 700, and 1800 N and the failure load. Paired t test was performed to assess the differences between two groups.
The failure mode of almost all defect model femora was consistent with that of the simulated type of intertrochanteric fractures. After the PFNA implantation, the failure mode of almost all stabilized femora was caused by new lateral wall fractures. The failure load of the lateral wall group for defect model femora was significantly higher than that of the medial wall group (p < 0.001). However, the difference disappeared after the PFNA was implanted (p = 0.990). The axial stiffness in all defect model femora showed the same results (p < 0.001). After the PFNA implantation, the axial stiffness of the lateral wall group remained higher than that of the medial wall group (p = 0.001). However, the axial stiffness of the lateral wall group showed that the femora removed from the lateral wall were higher than the PFNA-stabilized femora (p = 0.020). For the axial strain in the anterior wall after the PFNA implantation, the strain of the lateral wall group was significantly lower than that of the medial group (p = 0.003). Nevertheless, for the axial strain of the posterior wall after the PFNA implantation, the strain of the medial wall group was significantly lower than that of the lateral group (p < 0.001).
In summary, this study demonstrated that PFNA is an effective intramedullary fixation system for treating unstable intertrochanteric fractures. Compared with the lateral wall, the medial femoral wall is a more important part in the intertrochanteric region. We suggest that in treating intertrochanteric femoral fractures with medial wall fractures, the medial wall fragment should be reset and fixed as much as possible.
本研究的主要目的是调查人体尸体股骨转子间区域在内侧壁或外侧壁缺失与使用股骨近端抗旋髓内钉(PFNA)治疗后负荷和应变变化的差异。
在测量股骨近端区域的几何形状并建立内侧或外侧壁缺损股骨模型后,将六对新鲜冷冻的人体股骨随机分配到内侧壁组或外侧壁组。根据单腿站立模型施加轴向负荷,并在PFNA植入前后测量应变分布。在350、700和1800 N的负荷水平以及失效负荷下记录每个标本的应变。进行配对t检验以评估两组之间的差异。
几乎所有缺损模型股骨的失效模式与模拟的转子间骨折类型一致。PFNA植入后,几乎所有稳定股骨的失效模式均由新的外侧壁骨折引起。缺损模型股骨外侧壁组的失效负荷明显高于内侧壁组(p <0.001)。然而,PFNA植入后差异消失(p = 0.990)。所有缺损模型股骨的轴向刚度显示相同结果(p <0.001)。PFNA植入后,外侧壁组的轴向刚度仍高于内侧壁组(p = 0.001)。然而,外侧壁组的轴向刚度显示,去除外侧壁的股骨高于PFNA固定的股骨(p = 0.020)。对于PFNA植入后前壁的轴向应变,外侧壁组的应变明显低于内侧组(p = 0.003)。然而,对于PFNA植入后后壁的轴向应变,内侧壁组的应变明显低于外侧组(p <0.001)。
总之,本研究表明PFNA是治疗不稳定转子间骨折的一种有效的髓内固定系统。与外侧壁相比,股骨内侧壁是转子间区域更重要的部分。我们建议在治疗伴有内侧壁骨折的转子间股骨骨折时,应尽可能复位并固定内侧壁碎片。