Subramaniam Akila, Britt William J
Department of Obstetrics and Gynecology, Maternal-Fetal Medicine Division, Center for Women's Reproductive Health, Birmingham, Alabama.
Pediatric Division of Infectious Diseases, the University of Alabama at Birmingham, Birmingham, Alabama.
Clin Obstet Gynecol. 2018 Mar;61(1):157-176. doi: 10.1097/GRF.0000000000000335.
Bacterial, viral, and parasitic pathogens add significant morbidity and even mortality to pregnancy-with adverse effects extending to both the gravida and the newborn. Three herpesviruses deserve considerable attention given the effects of perinatal infection on obstetric outcomes, specifically maternal and neonatal morbidity. In the following review, we will provide a description of cytomegalovirus, herpes simplex virus, and varicella zoster virus. For each viral pathogen, we will describe the epidemiology, natural history, screening and diagnosis modalities, treatments, and implications for antepartum care. Furthermore, we will highlight future directions of work in reducing the morbidities associated with these viral pathogens.
细菌、病毒和寄生虫病原体增加了妊娠期间的显著发病率甚至死亡率，其不良影响延伸至孕妇和新生儿。鉴于围产期感染对产科结局的影响，尤其是对母婴发病率的影响，三种疱疹病毒值得高度关注。在以下综述中，我们将描述巨细胞病毒、单纯疱疹病毒和水痘带状疱疹病毒。对于每种病毒病原体，我们将描述其流行病学、自然史、筛查和诊断方式、治疗方法以及对产前护理的影响。此外，我们将强调在降低与这些病毒病原体相关的发病率方面未来的工作方向。
