Algoodkar Sharanabasappa, Kidangazhiathmana Ajithkumar, Rejani P P, Shaji K S
Department of Psychiatry, Sapthagiri Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, India.
Department of Dermatology and Venereology, Government Medical College, Kozhikode, Kerala, India.
Indian J Psychol Med. 2017 Nov-Dec;39(6):789-793. doi: 10.4103/IJPSYM.IJPSYM_364_17.
Individuals with HIV/AIDS are prone for psychiatric/psychological morbidities. Many studies have reported significantly higher prevalence of depression in people living with HIV/AIDS (PLWHA's) when compared to general population. However, there are only very few studies looking at the prevalence of depression in patients on antiretroviral therapy (ART).
To estimate the prevalance and factors associated with depression among clinically stable PLWHAs.
We used a cross-sectional study design to estimate the prevalence of depression and factors associated with it among clinically stable PLWHAs with CD4 cell count >400 cells/mm3 and on ART for >2 years. We assessed 100 PLWHAs and diagnosed depression using ICD-10 diagnostic criteria.
The prevalence of depression was 30% in this sample. Female gender, lack of family support, and HIV-positive status of the spouse were associated with depression in this study. Multiple logistic regression analysis showed lack of family support significantly associated with depression. High prevalence of depression and its association with stressful life circumstances even in individuals stable on ART points toward need for psychosocial interventions to improve metal health and well-being of these patients.
感染艾滋病毒/艾滋病的个体容易出现精神/心理疾病。许多研究报告称，与普通人群相比，艾滋病毒/艾滋病感染者（PLWHA）中抑郁症的患病率显著更高。然而，仅有极少数研究关注接受抗逆转录病毒疗法（ART）的患者中抑郁症的患病率。
评估临床病情稳定的艾滋病毒感染者中抑郁症的患病率及其相关因素。
我们采用横断面研究设计，评估CD4细胞计数>400个细胞/mm³且接受抗逆转录病毒治疗超过2年的临床病情稳定的艾滋病毒感染者中抑郁症的患病率及其相关因素。我们评估了100名艾滋病毒感染者，并使用国际疾病分类第10版（ICD-10）诊断标准诊断抑郁症。
该样本中抑郁症的患病率为30%。在本研究中，女性、缺乏家庭支持以及配偶的艾滋病毒阳性状态与抑郁症相关。多因素逻辑回归分析显示，缺乏家庭支持与抑郁症显著相关。即使在接受抗逆转录病毒治疗病情稳定的个体中抑郁症患病率较高且与压力性生活状况相关，这表明需要进行社会心理干预以改善这些患者的心理健康和幸福感。
